癌症患者的不良后果
原文发布日期:2020-07-31
英文摘要:
摘要翻译:
原文链接:
adverse outcomes in patients with cancer
In 84,246 consecutive Italians tested for SARS-CoV-2, we examined the prevalence of cancer and clinical outcomes of viral infection. Overall, 5.7% (4,789/84,246) had previously been diagnosed with cancer and, among the SARS-CoV-2-positive (CV2+ve) patients, 7.8% had a cancer diagnosis (723/9,275). Prevalence of cancer was not associated with risk of infection (odds ratio of 0.97; 95% confidence interval of 0.89–1.06). The proportion of CV2+ve people hospitalized was higher among patients with cancer (56.6 versus 34.4% among other people), and so was the proportion of deaths (14.7% versus 4.5%). The risk of adverse outcomes of SARS-CoV-2 infection was significantly higher for patients with cancer versus those without, particularly for males and older people.
在连续检测了84,246名意大利人感染新冠病毒(SARS-CoV-2)后,我们考察了癌症患病率及病毒感染的临床结果。总体而言,在这84,246名受试者中,有5.7%(即4,789人)曾被诊断出过癌症;而在新冠病毒阳性患者(CV2+ve)中,这一比例为7.8%(723人)。癌症的发病率与感染新冠病毒的风险之间并未显著关联(比值比为0.97;95%置信区间为0.89–1.06)。然而,在接受治疗的患者中,住院率在有癌症的患者中更高(56.6% vs 34.4%),死亡率也是如此(14.7% vs 4.5%)。对于新冠病毒感染而言,与未感染新冠病毒者相比,尤其是对男性和老年人而言,出现不良临床结果的风险显著升高。
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