文章：

前列腺癌的非常规疗法：好、坏还是有问题？

Unconventional therapy for prostate cancer: good, bad or questionable?

原文发布日期：2003-11-01

DOI: 10.1038/nrc1210

类型: Review Article

开放获取: 否

要点：

1. The protracted natural history and lack of curative therapy for advanced prostate cancer makes complementary and alternative medicine (CAM) attractive to patients.
2. CAM is as widely practiced as traditional medicine.
3. Antioxidant and hormonal influences of dietary and alternative therapies hold promise for the prevention and treatment of prostate cancer.
4. The lack of quality control of CAMs that are offered as dietary supplements makes them susceptible to adulteration.
5. New models for how to incorporate studies of CAM into chemoprevention and therapeutic trials are badly needed.

要点翻译：

1. 前列腺癌自然病程漫长且晚期缺乏有效疗法，这使得补充与替代医学（CAM）对患者具有吸引力。
2. CAM的实践应用与传统医学同样广泛。
3. 饮食疗法与替代医学所具有的抗氧化及激素调节作用，为前列腺癌的预防和治疗带来了希望。
4. 作为膳食补充剂销售的CAM产品缺乏质量控制，易存在掺假问题。
5. 亟需建立新模型将CAM研究纳入化学预防和治疗试验体系。

英文摘要：

Complementary and alternative medicine (CAM) encompasses a wide range of interventions that are often used for the prevention and treatment of malignant disease. As prostate cancer is characterized by strong dietary influences, a long disease latency period and limited treatment strategies for advanced disease, many patients turn to CAM with the belief that they represent a viable therapeutic option that is free of adverse side effects. Although the efficacy of many CAM therapies seems compelling, definitive studies are underway and the potentially harmful effects of these 'natural' interventions need to be recognized.

摘要翻译： 

补充与替代医学（CAM）涵盖了广泛用于恶性肿瘤预防和治疗的多种干预措施。由于前列腺癌明显受饮食影响、疾病潜伏期长，且晚期治疗手段有限，许多患者转而求助CAM，认为这些疗法有效且无副作用。尽管不少CAM疗法看似疗效显著，相关确证研究仍在进行，其“天然”干预措施可能带来的危害也需被正视。

原文链接：

Unconventional therapy for prostate cancer: good, bad or questionable?