文章：

“放射学分级”在中央软骨肿瘤术前评估中的应用

“Radiological Grading” for Preoperative Assessment of Central Cartilaginous Tumors

原文发布日期：7 January 2026

DOI: 10.3390/cancers18020193

类型: Article

开放获取: 是

英文摘要：

In the treatment of musculoskeletal tumors, surgeons sometimes experience discrepancies in the histological grade between the preoperative biopsy and resected tumor specimen, and the frequency of the histological discrepancies in cartilaginous tumors is higher than that in other bone tumors. For cartilaginous tumors, new diagnostic tools or methods for the prediction of histological grades are required to determine appropriate surgical procedures for each patient. Several radiological findings have been reported to be useful in differentiating benign cartilaginous tumors, atypical cartilaginous tumors/grade 1 chondrosarcomas, and high-grade chondrosarcomas. Furthermore, recent studies have shown the high accuracy of radiological scoring systems that integrate several radiological findings to predict the histological grades of cartilaginous tumors. Radiomics, which converts features in radiological images into quantitative data, enables the comprehensive analysis of cartilaginous tumors. Recent reports suggest that radiological diagnoses are highly reliable compared with preoperative histological diagnoses for predicting the final histological diagnosis. Based on previous reports, “radiological grading,” i.e., the prediction of histological aggressiveness using radiological modalities, can be important for determining the surgical procedure, in addition to “histological grading.” This review article discusses radiological findings, integrated radiological scoring systems, and radiomics-based predictions of histological grades in cartilaginous tumors.

摘要翻译： 

在肌肉骨骼肿瘤的治疗中，外科医生有时会遇到术前活检与切除肿瘤标本的组织学分级不一致的情况，且软骨性肿瘤中出现组织学分型差异的频率高于其他骨肿瘤。针对软骨性肿瘤，需要新的诊断工具或方法来预测组织学分级，以便为每位患者制定合适的手术方案。已有研究报道多种影像学发现可用于区分良性软骨性肿瘤、非典型软骨性肿瘤/1级软骨肉瘤以及高级别软骨肉瘤。此外，近期研究表明，整合多项影像学特征的放射学评分系统在预测软骨性肿瘤组织学分级方面具有较高准确性。放射组学技术可将影像图像特征转化为定量数据，实现对软骨性肿瘤的全面分析。最新报告显示，在预测最终组织学诊断方面，影像学诊断相较于术前组织学诊断具有更高的可靠性。既往研究表明，除“组织学分级”外，“影像学分级”（即通过影像学手段预测肿瘤组织学侵袭性）对确定手术方案至关重要。本综述将探讨软骨性肿瘤的影像学特征、综合放射学评分系统及基于放射组学的组织学分级预测方法。

原文链接：

“Radiological Grading” for Preoperative Assessment of Central Cartilaginous Tumors