文章：

在自我采样干预前，HIV感染女性对人乳头瘤病毒自我采样的态度研究

Human Papillomavirus Self-Sampling Attitudes Amongst Women Living with HIV Prior to a Self-Sampling Intervention

原文发布日期：19 December 2025

DOI: 10.3390/cancers18010014

类型: Article

开放获取: 是

英文摘要：

Background/Objectives: Our objective was to determine the acceptability of and attitudes towards HPV self-sampling among women with HIV and investigate any associations between self-sampling attitudes and participant demographic and clinical characteristics.Methods:Women with HIV aged 18–45 were given a description of HPV self-sampling and instructions on how to self-collect the sample. Participants completed a questionnaire assessing their perceptions of the acceptability and comfort of HPV self-sampling before using the self-sampling methodology. Responses were based on a 5-point Likert scale (strongly agree to strongly disagree) for each statement. Participants’ characteristics were included in bivariate analysis. Chi-square and Fisher’s exact tests were used to assess associations between questionnaire results and participant characteristics.Results: Of the 117 completed questionnaires, 79.6% of participants had a CD4+ T cell count ≥ 500 cells/mm3. Participants’ median age was 39 (IQR 34–43). One hundred participants (85.5%) felt confident they could collect their samples correctly, and 77.8% did not think they would experience difficulties with self-collection. Most participants (68.4%) preferred to self-collect their sample instead of provider-collected sampling. Ninety-six participants (82.1%) agreed they would likely use self-collection methods for future cervical screening. Many participants were concerned about receiving a positive HPV result (68.4%), passing HPV on to their partner(s) (75.7%), and disclosing their HPV status to friends/family (49.6%).Conclusions: Women with HIV seem to be accepting of HPV self-sampling as a cervical cancer screening methodology; however, many participants were concerned about the implications associated with a positive HPV test result.

摘要翻译： 

背景/目的：本研究旨在评估HIV感染女性对人乳头瘤病毒（HPV）自我采样的接受度及相关态度，并探讨自我采样态度与参与者人口学及临床特征之间的关联。方法：向18-45岁HIV感染女性提供HPV自我采样说明及操作指导。在使用自我采样方法前，参与者需填写问卷评估其对HPV自我采样的接受度与舒适度认知。各项陈述采用李克特五级量表（从"非常同意"到"非常不同意"）进行评价。通过双变量分析纳入参与者特征数据，采用卡方检验与费希尔精确检验分析问卷结果与参与者特征间的关联性。结果：在117份有效问卷中，79.6%参与者的CD4+ T细胞计数≥500个/立方毫米。参与者中位年龄为39岁（四分位距34-43岁）。85.5%（100名）参与者对正确采集样本具有信心，77.8%认为不会在自我采样过程中遇到困难。68.4%的参与者更倾向于自我采样而非医护人员采样。82.1%（96名）参与者表示未来宫颈筛查中可能采用自我采样方法。多数参与者对以下情况表示担忧：收到HPV阳性结果（68.4%）、将HPV传染给伴侣（75.7%）以及向亲友披露HPV感染状况（49.6%）。结论：HIV感染女性对HPV自我采样作为宫颈癌筛查方法表现出较高接受度，但多数参与者对HPV阳性结果可能带来的影响存在顾虑。

原文链接：

Human Papillomavirus Self-Sampling Attitudes Amongst Women Living with HIV Prior to a Self-Sampling Intervention