文章：

卵巢癌的早期检测与预防

Early Detection and Prevention of Ovarian Cancer

原文发布日期：16 December 2025

DOI: 10.3390/cancers17244006

类型: Article

开放获取: 是

英文摘要：

Background/Objectives: Epithelial ovarian cancer (EOC) encompasses ovarian, fallopian tube and peritoneal malignancies. It is a deadly disease and is rarely cured when diagnosed at advanced stages. Early-stage disease is often curable, but clinicians and researchers have been stymied in their attempts to reliably screen for this disease, even in high-risk populations. Effective prevention of ovarian cancer is usually limited to the use of combined oral contraceptives and removal of the ovaries and fallopian tubes.Methods and Results: We aim to review the current guidelines and the evidence reported for both the early detection and prevention of ovarian cancer. Novel imaging techniques, biomarkers, and surgical advances will be discussed.Conclusions: This review will offer (a) an understanding of the epidemiology of EOC (b) analysis and a discussion of relevant molecular markers that might be exploited for more accurate early detection (c) medical and surgical methods to prevent ovarian cancer.

摘要翻译： 

背景/目的：上皮性卵巢癌（EOC）包括卵巢癌、输卵管癌和腹膜癌。这是一种致命性疾病，若在晚期诊断，则很少能治愈。早期疾病通常可以治愈，但临床医生和研究人员在尝试可靠筛查该疾病方面一直受阻，即使在高风险人群中也是如此。卵巢癌的有效预防通常仅限于使用复方口服避孕药以及切除卵巢和输卵管。 方法与结果：我们旨在回顾当前关于卵巢癌早期检测和预防的指南及报告证据。本文将讨论新型成像技术、生物标志物以及外科手术进展。 结论：本综述将提供（a）对EOC流行病学的理解；（b）对可能用于更准确早期检测的相关分子标志物的分析与讨论；（c）预防卵巢癌的医学和外科方法。

原文链接：

Early Detection and Prevention of Ovarian Cancer