Background/Objectives: To determine whether long-term oncological follow-up is required following fertility-sparing surgery (FSS) for mucinous borderline ovarian tumours (MBOTs).Methods: A retrospective cohort study set in the tertiary gynaecology oncology centre at Imperial College Healthcare NHS Trust. Patients included were those under follow-up post-surgery for an MBOT in the ovarian clinic from 2007 to 2025. Rate of recurrence was compared amongst patients who underwent ovarian cystectomy, unilateral salpingo-oophorectomy (USO) or bilateral salpingo-oophorectomy (BSO) +/− hysterectomy.Results: From 74 patients diagnosed with MBOT, 36.5% (27/74) underwent BSO +/− hysterectomy and 63.5% (47/74) had FSS. Of the patients who underwent FSS, 59.6% (28/47) had an initial USO and 40.4% (19/47) underwent ovarian cystectomy. Subsequently, 63.2% (12/19) of patients who initially had ovarian cystectomy proceeded with completion USO, leading to a total of 40 USOs performed. There were no recurrences following BSO +/− hysterectomy, primary USO or completion USO after a median follow-up of 49.0, 65.5 and 48.0 months, respectively. Of the patients who underwent ovarian cystectomy, 15.8% (3/19) were found to have residual MBOT (n = 1) two months post-cystectomy or MBOT recurrence (n = 2) at 10- and 66-months post-cystectomy, all diagnosed at USO. There is a significant association between ovarian cystectomy and disease recurrence (Fisher’s exact testp= 0.015).Conclusions: Patients of reproductive age who undergo USO for a MBOT can be offered a reduced follow-up schedule as the risk of recurrence is very low. In contrast, patients who are managed by ovarian cystectomy have a higher risk of recurrence and require long-term surveillance monitoring.
背景/目的：探讨黏液性交界性卵巢肿瘤（MBOT）患者接受保留生育功能手术（FSS）后是否需要进行长期肿瘤学随访。 方法：本研究为回顾性队列研究，在帝国理工学院医疗保健NHS信托基金会的三级妇科肿瘤中心开展。研究对象为2007年至2025年间在卵巢专科门诊接受MBOT手术后进行随访的患者。比较接受卵巢囊肿切除术、单侧输卵管卵巢切除术（USO）或双侧输卵管卵巢切除术（BSO）±子宫切除术患者的复发率。 结果：在74例确诊为MBOT的患者中，36.5%（27/74）接受了BSO±子宫切除术，63.5%（47/74）接受了FSS。在接受FSS的患者中，59.6%（28/47）初次手术为USO，40.4%（19/47）接受了卵巢囊肿切除术。随后，63.2%（12/19）初次接受卵巢囊肿切除术的患者进行了补充性USO，使得USO总例数达到40例。在中位随访时间分别为49.0、65.5和48.0个月后，接受BSO±子宫切除术、初次USO或补充性USO的患者均未出现复发。在接受卵巢囊肿切除术的患者中，15.8%（3/19）在术后两个月发现残留MBOT（n=1）或在术后10个月和66个月出现MBOT复发（n=2），所有病例均在USO手术时确诊。卵巢囊肿切除术与疾病复发之间存在显著相关性（Fisher精确检验p=0.015）。 结论：对于因MBOT接受USO的育龄期患者，由于复发风险极低，可考虑采用简化随访方案。相比之下，接受卵巢囊肿切除术治疗的患者复发风险较高，需要进行长期监测随访。
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