文章：

泪囊肿瘤：基于组织学类型的文献综述

Lacrimal Sac Tumors: A Histotype-Driven Literature Review

原文发布日期：20 November 2025

DOI: 10.3390/cancers17223718

类型: Article

开放获取: 是

英文摘要：

Objectives: Because of their rarity, lacrimal sac tumors (LSTs) are challenging to diagnose and treat. We herein provide an overview of the recent literature. Methods: A scoping search of the Cochrane library, PubMed and Google Scholar database in the last 5 years was conducted. Three independent reviewers extracted data, and the findings were summarized due to study heterogeneity. Results: A total of 55 articles were included. LST histology is diverse and there is no commonly accepted staging system. Recent discoveries in their biology are offering new treatment strategies but exclusive endoscopic resections remain feasible in only very limited cases of non-aggressive LSTs. Conclusion: LSTs require a high index of suspicion because of their rarity. A histotype-driven treatment plan must be carefully prepared, but complete excision remains the cornerstone of treatment in all cases.

摘要翻译： 

目的：由于泪囊肿瘤（LSTs）较为罕见，其诊断与治疗颇具挑战性。本文旨在对近期相关文献进行系统性综述。方法：对过去五年内Cochrane图书馆、PubMed及Google Scholar数据库进行范围检索。由三位独立评审员提取数据，并针对研究异质性对结果进行归纳总结。结果：共纳入55篇文献。泪囊肿瘤组织学类型多样，目前尚无公认的分期标准。近期生物学研究进展为治疗提供了新策略，但内镜下完全切除术仅适用于极少数非侵袭性泪囊肿瘤病例。结论：鉴于泪囊肿瘤的罕见性，临床诊断需保持高度警惕。治疗需根据组织学类型制定个体化方案，但所有病例的治疗核心仍在于实现肿瘤的完整切除。

原文链接：

Lacrimal Sac Tumors: A Histotype-Driven Literature Review