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文章:

体重指数对早期子宫内膜癌机器人手术结局的影响:一项回顾性队列研究

Impact of Body Mass Index on Robotic Surgery Outcomes in Early-Stage Endometrial Cancer: A Retrospective Cohort Study

原文发布日期:5 November 2025

DOI: 10.3390/cancers17213570

类型: Article

开放获取: 是

 

英文摘要:

Background/Objectives: Obesity is a well-established risk factor for endometrial cancer and presents challenges for surgical management. Robotic-assisted surgery offers a minimally invasive approach with potential benefits for obese patients. This study sought to assess the impact of body mass index (BMI) on surgical performance and short-term outcomes in patients undergoing robotic surgery for early-stage endometrial cancer, focusing on follow-up and perioperative treatment.Methods: A retrospective analysis was conducted on 54 patients with early-stage endometrial cancer who underwent a robotic total hysterectomy, bilateral salpingo-oophorectomy, and indocyanine green sentinel lymph node biopsy between January 2021 and December 2024 at two tertiary centers. Patients were stratified by body mass index. Surgical variables, sentinel lymph node detection rates, peri- and postoperative complications, length of hospital stay, and short-term oncologic outcomes were assessed. Statistical comparisons were performed using ANOVA, chi-square tests, and Pearson’s correlation analysis.Results: The mean patient age was 59.7 years, with a mean BMI of 31.1 kg/m2. Bilateral sentinel lymph node detection was successful in 87% of cases, with no significant differences between BMI groups. Console time, hospital stay, and complication rates were comparable across BMI categories. Console time positively correlated with the number of lymph nodes removed (r = 0.302,p= 0.026), but not with BMI. At a mean follow-up of 24.4 months, no recurrences were observed.Conclusions: Robotic surgery for early-stage endometrial cancer is safe and effective regardless of BMI, including in patients with Class III obesity. BMI does not negatively impact surgical or short-term oncologic outcomes, supporting robotic surgery as an optimal approach in obese endometrial cancer patients.

 

摘要翻译: 

**背景/目的:** 肥胖是子宫内膜癌的明确危险因素,并为手术治疗带来挑战。机器人辅助手术作为一种微创方法,对肥胖患者具有潜在益处。本研究旨在评估体重指数对早期子宫内膜癌患者接受机器人手术时的手术表现及短期结局的影响,重点关注随访及围手术期处理。 **方法:** 对2021年1月至2024年12月期间在两所三级医疗中心接受机器人辅助全子宫切除术、双侧输卵管卵巢切除术及吲哚菁绿前哨淋巴结活检的54例早期子宫内膜癌患者进行回顾性分析。患者按体重指数分层。评估了手术相关变量、前哨淋巴结检出率、围手术期及术后并发症、住院时间及短期肿瘤学结局。采用方差分析、卡方检验和皮尔逊相关分析进行统计学比较。 **结果:** 患者平均年龄为59.7岁,平均体重指数为31.1 kg/m²。87%的病例成功实现双侧前哨淋巴结检出,不同体重指数组间无显著差异。控制台操作时间、住院时间和并发症发生率在各体重指数类别间具有可比性。控制台操作时间与切除的淋巴结数量呈正相关(r = 0.302, p = 0.026),但与体重指数无关。在平均24.4个月的随访期内,未观察到复发。 **结论:** 无论体重指数如何,包括III级肥胖患者在内,机器人手术治疗早期子宫内膜癌均是安全有效的。体重指数未对手术或短期肿瘤学结局产生负面影响,这支持了机器人手术作为肥胖子宫内膜癌患者最佳治疗方法的观点。

 

 

原文链接:

Impact of Body Mass Index on Robotic Surgery Outcomes in Early-Stage Endometrial Cancer: A Retrospective Cohort Study

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