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文章:

基于MRI的影像组学在鼻窦癌管理中的作用:一项范围综述

Role of MRI-Based Radiomics in Sinonasal Cancer Management: A Scoping Review

原文发布日期:14 October 2025

DOI: 10.3390/cancers17203313

类型: Article

开放获取: 是

 

英文摘要:

Background/Objectives:Malignant tumors of the sinonasal tract are rare, accounting for approximately 3–5% of all head and neck tumors. Despite recent advances in therapy, overall survival in sinonasal cancer remains limited, with local recurrence representing the leading cause of treatment failure. Consequently, the preoperative identification of patients at higher risk of recurrence or developing more aggressive tumors is of critical importance to guide treatment strategies and improve outcomes. The aim of this review is to analyze the results of the most recent literature studying the use of radiomics in malignant sinonasal tumors.Methods:A comprehensive literature review was conducted using the PubMed/MEDLINE, EMBASE and Cochrane Library databases, in accordance with the PRISMA review criteria (from 2020 to July 2025).Results:The final analysis comprised a total of five articles and 629 patients. At present, radiomics in sinonasal cancer is mainly applied to the prediction of Ki-67 expression, the early assessment of recurrence risk, and the evaluation of response to induction chemotherapy.Conclusions:The results of this review indicate that radiomics has the potential to play an important role in the management of sinonasal malignant tumors. However, further research is necessary to confirm these findings.

 

摘要翻译: 

背景/目的:鼻腔鼻窦恶性肿瘤较为罕见,约占头颈部肿瘤的3-5%。尽管近年来治疗方法有所进展,但鼻腔鼻窦癌的总体生存率仍然有限,局部复发是治疗失败的主要原因。因此,术前识别复发风险较高或可能发展为更具侵袭性肿瘤的患者,对于指导治疗策略和改善预后至关重要。本综述旨在分析近期关于影像组学在鼻腔鼻窦恶性肿瘤中应用的研究文献结果。方法:根据PRISMA综述标准(2020年至2025年7月),使用PubMed/MEDLINE、EMBASE和Cochrane图书馆数据库进行了全面的文献综述。结果:最终分析共纳入5篇文献,涉及629例患者。目前,影像组学在鼻腔鼻窦癌中的应用主要集中在预测Ki-67表达、早期评估复发风险以及评估诱导化疗反应等方面。结论:本综述结果表明,影像组学在鼻腔鼻窦恶性肿瘤的诊疗中具有发挥重要作用的潜力,但仍需进一步研究以证实这些发现。

 

 

原文链接:

Role of MRI-Based Radiomics in Sinonasal Cancer Management: A Scoping Review

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