Background: Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of indolent or aggressive lymphoproliferative neoplasms arising from lymph nodes or in extranodal locations. Computed tomography (CT) is the imaging modality of choice, while the definitive diagnosis is confirmed by analyzing tissue samples. The aim of this study was to determine the correlation between CT characteristics and histopathological types of abdominal lymphomas. Methods: A retrospective cross-sectional study included 119 patients with histopathologically confirmed abdominal lymphomas who underwent CT of the abdomen and pelvis prior to treatment. The following CT parameters were extracted: morphological presentation (enlarged lymph nodes/conglomerates, solid mass/masses, gastrointestinal wall thickening, abdominal organ involvement, intra- and extraperitoneal infiltrates), location, two-dimensional size, propagation if present, and postcontrast enhancement. Results: Enlarged lymph nodes were a slightly more common CT morphological appearance in the indolent B NHL group, while gastrointestinal (GI) wall thickening, solid masses, and infiltrates were more frequent in the aggressive B NHL group (p= 0.0256). Aggressive B-cell lymphomas had larger size at time of diagnosis compared to other types (p= 0.0436). CT postcontrast enhancement showed lymphomas originating from the gastrointestinal tract, which presented as wall thickening, had the highest enhancement (p= 0.0065 andp= 0.0485). Conclusions: Observed differences in abdominal lymphomas’ histopathological and imaging characteristics including location/origin, CT morphological appearance, and postcontrast enhancement revealed that extranodal lymphomas were more often of the aggressive B-cell type, aggressive B-cell types were larger, and GI tract lymphomas showed the most prominent enhancement. These findings can help in the diagnostic process and enable better management of lymphomas.
背景：非霍奇金淋巴瘤（NHL）是一组异质性的惰性或侵袭性淋巴增殖性肿瘤，可原发于淋巴结或结外部位。计算机断层扫描（CT）是首选的影像学检查方法，而最终诊断需通过组织样本分析确认。本研究旨在探讨腹部淋巴瘤的CT特征与组织病理学类型之间的相关性。方法：一项回顾性横断面研究纳入了119例经组织病理学确诊的腹部淋巴瘤患者，这些患者在治疗前均接受了腹部和盆腔CT检查。提取的CT参数包括：形态学表现（淋巴结肿大/融合、实性肿块、胃肠道壁增厚、腹部器官受累、腹膜内外浸润）、位置、二维尺寸、是否存在播散以及增强后强化情况。结果：在惰性B细胞NHL组中，淋巴结肿大是稍为常见的CT形态学表现，而在侵袭性B细胞NHL组中，胃肠道壁增厚、实性肿块和浸润更为常见（p=0.0256）。与其他类型相比，侵袭性B细胞淋巴瘤在诊断时体积更大（p=0.0436）。CT增强扫描显示，起源于胃肠道并表现为壁增厚的淋巴瘤强化程度最高（p=0.0065和p=0.0485）。结论：观察到的腹部淋巴瘤在组织病理学和影像学特征上的差异，包括位置/起源、CT形态学表现和增强后强化特点，表明结外淋巴瘤更常为侵袭性B细胞类型，侵袭性B细胞类型体积更大，且胃肠道淋巴瘤强化最为显著。这些发现有助于诊断过程，并有助于更好地管理淋巴瘤。
肿瘤(癌症)患者之家