Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with curative surgical interventions feasible for a minority of patients. This review highlights recent advances in thermal (e.g., radiofrequency ablation, microwave ablation, and cryoablation) and nonthermal (e.g., ethanol ablation and irreversible electroporation) ablative modalities as curative-intent alternatives to surgery. Evolving applications of transcatheter intra-arterial radioembolization (TARE) with ablative dosimetry will be explored, and histotripsy, an emerging technology, will be introduced.
肝细胞癌是全球癌症相关死亡的主要原因,仅少数患者适合接受根治性手术治疗。本综述重点探讨了热消融(如射频消融、微波消融和冷冻消融)与非热消融(如乙醇消融和不可逆电穿孔)作为手术替代方案的根治性治疗进展。同时将探讨具有消融剂量学的经导管动脉内放射栓塞术的新兴应用,并介绍一种新兴技术——组织切片术。
Recent Advances in Ablative Therapies for Hepatocellular Carcinoma