文章：

胰腺与十二指肠肿瘤的外科治疗策略

Surgical Strategies for Tumors of the Pancreas and Duodenum

原文发布日期：22 September 2025

DOI: 10.3390/cancers17183091

类型: Article

开放获取: 是

英文摘要：

The recommended surgery for pancreatic tumors is dependent on the diagnosis. For pancreatic adenocarcinoma, duodenal, and ampullary adenocarcinoma, a Whipple pancreaticoduodenectomy with lymph node dissection is recommended. For small < 2 cm or non-imageable gastrinomas, duodenal transillumination, duodenotomy, duodenal tumor excision and adjacent lymphadenectomy is recommended. For large > 3 cm gastrinomas, a Whipple pancreaticoduodenectomy with adjacent lymph node dissection is recommended. For small 1–2 cm insulinomas, intraoperative ultrasound with enucleation is recommended. If the patient with gastrinoma, insulinoma, or multiple nonfunctional NETs occurs in the setting of MEN-1, a subtotal pancreatectomy with or without splenectomy with enucleation of pancreatic head tumors is recommended, with adjacent lymph node dissection. The detail of each procedure is described with illustrations.

摘要翻译： 

胰腺肿瘤的手术方案选择取决于具体诊断。对于胰腺腺癌、十二指肠癌及壶腹腺癌，推荐采用胰十二指肠切除术联合淋巴结清扫术。针对直径小于2厘米或影像学难以显示的胃泌素瘤，建议实施十二指肠透照检查、十二指肠切开术、肿瘤切除术及区域淋巴结清扫。对于直径大于3厘米的胃泌素瘤，则应行胰十二指肠切除术联合区域淋巴结清扫。对于1-2厘米的小型胰岛素瘤，推荐术中超声引导下肿瘤剜除术。若胃泌素瘤、胰岛素瘤或多发无功能神经内分泌肿瘤患者同时伴发多发性内分泌腺瘤病1型，建议实施保留或不保留脾脏的次全胰腺切除术，同时剜除胰头部肿瘤并行区域淋巴结清扫。各术式具体操作细节均配有图示说明。

原文链接：

Surgical Strategies for Tumors of the Pancreas and Duodenum