文章：

定义非直肠癌盆腔廓清术标准数据报告：当前数据报告的系统性综述

Defining Standard Data Reporting in Pelvic Exenterations for Non-Rectal Cancers: A Systematic Review of Current Data Reporting

原文发布日期：18 September 2025

DOI: 10.3390/cancers17183049

类型: Article

开放获取: 是

英文摘要：

Introduction: Pelvic exenteration (PEx) was first described in the 1940s as a palliative procedure in managing cervical cancer. Since then, advancements in perioperative care have transformed the options available to patients. This highly morbid procedure now offers a “cure” in a select cohort of patients with locally advanced and recurrent pelvic cancers. The large volume of literature in this field has resulted in a heterogeneity of data reporting, making comparative analysis extremely difficult. As such, we set out to examine the current literature and identify currently reported outcomes to guide development of a core information set (CIS) for data reporting for PEx in non-rectal cancers. Methods: A systematic review was carried out. Studies reporting on outcomes following PEx for advanced and recurrent gynecological, urological, and other non-rectal malignancies were included. Standardized outcomes were extracted and mapped to pre-determined domains. Results: Forty-four studies were found to meet our inclusion criteria. A total of 1735 data elements (DEs) were extracted verbatim, and these were assimilated into 111 standard DEs across nine domains. A wide range of reporting frequencies was observed, with the pathological domain containing the highest overall frequencies of DE reporting. Conversely, patient-reported and functional outcomes were noted to be the domain with the lowest frequency. Conclusions: This review highlights recent trends of increased reporting in the field of PEx and how this had invariably resulted in heterogeneous data reporting. We aim to guide the development of a CIS for reporting in non-rectal pelvic malignancies to help standardize future reporting.

摘要翻译： 

引言：盆腔廓清术（PEx）于20世纪40年代首次被描述为治疗宫颈癌的姑息性手术。此后，围手术期护理的进步为患者提供了更多治疗选择。这一高致残率手术现已成为局部晚期和复发性盆腔癌特定患者群体的“根治性”治疗手段。该领域大量文献导致数据报告存在异质性，使得比较分析极为困难。为此，我们系统梳理现有文献，识别当前报告结果，以指导建立非直肠癌盆腔廓清术数据报告的核心信息集（CIS）。方法：本研究采用系统综述方法，纳入针对晚期及复发性妇科、泌尿系统及其他非直肠恶性肿瘤行盆腔廓清术后结局的文献。提取标准化结局指标并归类至预设领域。结果：共44项研究符合纳入标准。逐字提取1735个数据元素（DEs），最终整合为9大领域的111个标准化DEs。各领域报告频率差异显著，其中病理学领域DEs报告频率最高。相反，患者报告结局和功能结局领域报告频率最低。结论：本综述揭示了盆腔廓清术领域报告数量增长的趋势，以及由此必然导致的数据报告异质性。我们旨在指导建立非直肠盆腔恶性肿瘤报告的核心信息集，以推动未来报告标准化进程。

原文链接：

Defining Standard Data Reporting in Pelvic Exenterations for Non-Rectal Cancers: A Systematic Review of Current Data Reporting