Immature teratoma of the ovary is a rare condition primarily affecting young women and constitutes a significant proportion of ovarian cancer cases in adolescents and young adults. It is commonly diagnosed at stage I, though advanced-stage disease is not infrequent. Accurate diagnosis and a fertility-sparing approach are central to the management of this condition, as many affected women retain, or have yet to develop, a desire for childbearing. However, due to the rarity of this disease, management is often guided by retrospective data derived from subanalyses of studies on malignant ovarian germ cell tumors, which can complicate the treatment of these patients once diagnosed. The aim of this review is to summarize the current evidence on immature teratoma of the ovary, considering it as a distinct clinical and pathological entity.
卵巢未成熟畸胎瘤是一种罕见疾病,主要影响年轻女性,在青少年和年轻成人卵巢癌病例中占相当比例。该病通常在Ⅰ期被诊断,但晚期病例亦不少见。由于许多患者仍保留或尚未形成生育意愿,精确诊断与保留生育功能的治疗方案成为疾病管理的核心。然而,由于该病罕见性,其治疗策略常依赖于恶性卵巢生殖细胞肿瘤研究的回顾性亚组分析数据,这可能导致确诊患者的治疗复杂化。本综述旨在将卵巢未成熟畸胎瘤作为独立的临床病理实体,系统总结当前相关证据。