Background/Objectives:Many cancer survivors continue to experience persistent symptoms such as pain, fatigue, and depression. Exercise and increasing physical activity (PA) are recommended as methods that can help alleviate these symptoms. However, maintaining regular exercise can be difficult due to the challenge of maintaining motivation. This secondary analysis uses data from a randomized controlled pilot study that examines the feasibility of the technology-enhanced combined exercise and other nonpharmacological interventions, such as the TEHEplus program, in managing symptoms. The program used mobile technologies and sent weekly physical performance reports to maintain engagement. In this study, we aimed to examine the impact of weekly physical performance reports on daily symptoms and PA and explored characteristics as moderators.Methods:This secondary analysis included participants who completed the 12-week TEHEplus program. Daily data of steps (PA), sleep duration, and symptoms (rated on a 4-point scale) were collected for 84 days. Mixed-effects and lagged regression models were used to assess the impact of weekly physical performance reports and the moderating effects of baseline characteristics.Results:Seventy-seven survivors of solid tumor cancer (mean age, 59.79,SD= 12.17) were analyzed. During this 84-day period, participants reported a reduction in low energy (B= −0.003,p= 0.004). Step counts increased by an average of 141 steps immediately after each weekly report (B= 140.857,p= 0.027). An increase of 5000 steps on the prior day was related to decreasing pain (B= −0.047,p< 0.001) and fatigue/low energy (B= −0.082,p< 0.001). Two additional hours of prior-night sleep worsened pain (B= 0.029,p= 0.001) and fatigue/low energy (B= 0.027,p= 0.002). Gender, employment, race, caregiver, and type of treatments moderate the relationship between daily PA, sleep (B= −0.131~0.078,ps< 0.05).Conclusions:Weekly physical performance reports promoted PA, which possibly led to self-reported improvement of symptoms. Higher PA was associated with better self-report symptoms, but longer sleep duration was associated with worsened symptoms, suggesting the need for future studies. The moderating effects suggested that tailoring interventions to individual profiles may enhance the program’s effectiveness.
背景/目的：许多癌症幸存者仍持续经历疼痛、疲劳及抑郁等症状。运动与增加体力活动被推荐为缓解这些症状的有效方法，但维持规律运动常因动力不足而难以坚持。本研究基于一项随机对照预试验的二次分析，探讨技术增强型综合运动与非药物干预（如TEHEplus方案）在症状管理中的可行性。该方案运用移动技术，通过发送每周体能报告以维持参与者参与度。本研究旨在分析每周体能报告对日常症状与体力活动的影响，并探索基线特征的调节作用。 方法：本次二次分析纳入完成12周TEHEplus方案的参与者。研究连续84天收集每日步数（体力活动）、睡眠时长及症状评分（采用4级量表）。采用混合效应模型与滞后回归模型评估每周体能报告的影响及基线特征的调节效应。 结果：共分析77名实体瘤癌症幸存者（平均年龄59.79岁，标准差12.17）。在84天观察期内，参与者报告低能量症状减轻（B=-0.003，p=0.004）。每周报告发布后次日步数平均增加141步（B=140.857，p=0.027）。前一日步数每增加5000步与疼痛减轻（B=-0.047，p<0.001）及疲劳/低能量症状缓解（B=-0.082，p<0.001）相关。而前夜睡眠每增加两小时则与疼痛加重（B=0.029，p=0.001）及疲劳/低能量症状恶化（B=0.027，p=0.002）相关。性别、就业状况、种族、照护者身份及治疗类型对每日体力活动、睡眠与症状的关系具有调节作用（B=-0.131~0.078，ps<0.05）。 结论：每周体能报告能促进体力活动，可能由此带来症状的自我报告改善。较高体力活动水平与更好的自我报告症状相关，但较长睡眠时间与症状恶化相关，这提示需开展进一步研究。调节效应表明，根据个体特征定制干预措施可能提升方案效果。
肿瘤(癌症)患者之家