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文章:

经膀胱单孔机器人辅助根治性前列腺切除术后早期尿控与勃起功能恢复:单中心初步经验

Early Continence and Erectile Function Recovery Following Transvesical Single-Port Robot-Assisted Radical Prostatectomy: Initial Single Institution Experience

原文发布日期:27 August 2025

DOI: 10.3390/cancers17172793

类型: Article

开放获取: 是

 

英文摘要:

Background/Objectives: Early recovery of urinary continence and sexual function remains a key focus following radical prostatectomy. The transvesical single-port robot-assisted radical prostatectomy (SP-TV-RARP) approach is a novel technique with very limited evidence that has been suggested to preserve the Retzius space and allow extraperitoneal access through the bladder. We aimed to evaluate early functional and oncologic outcomes following SP-TV-RARP at a single academic institution.Methods: We retrospectively reviewed 21 patients who underwent SP-TV-RARP by a single surgeon between September 2024 and May 2025. Continence is defined as being pad-free, and return of erectile function is defined as having erections sufficient for penetration. Functional and oncologic outcomes were assessed using clinical follow-up documentation and analyzed with Kaplan–Meier analysis.Results: The median patient age was 65 years, and 52.4% had pT3 disease. Positive surgical margins were observed in 62% overall and 30% in men with organ-confined disease. No intraoperative or 30-day postoperative complications occurred. Approximately 43% of patients achieved continence within one day of urethral catheter removal, with 75% of patients being pad-free at 3 months. Median SHIM and AUA-SS scores did not significantly decline at 3 months compared to baseline. The median time to recovery of erectile function was 69 days, and 67% recovered at the last follow-up. Biochemical recurrence occurred in 2 patients (15.4%) within 6 months.Conclusions: SP-TV-RARP appears safe and may facilitate early return of urinary continence and erectile function. Although inferior oncologic outcome is a potential concern during early adoption, functional outcomes were favorable. Further prospective evaluation is warranted to confirm long-term oncologic efficacy.

 

摘要翻译: 

背景/目的:根治性前列腺切除术后尿控功能与性功能的早期恢复仍是关键关注点。经膀胱单孔机器人辅助根治性前列腺切除术(SP-TV-RARP)是一种创新术式,现有证据极为有限,该技术被认为可保留Retzius间隙并通过膀胱实现腹膜外入路。本研究旨在评估单一学术机构实施SP-TV-RARP的早期功能与肿瘤学结局。 方法:回顾性分析2024年9月至2025年5月期间由同一位外科医师实施的21例SP-TV-RARP患者。尿控定义为无需使用尿垫,勃起功能恢复定义为达到足以完成性交的勃起硬度。通过临床随访记录评估功能与肿瘤学结局,并采用Kaplan-Meier法进行分析。 结果:患者中位年龄65岁,52.4%存在pT3期病变。总体手术切缘阳性率为62%,器官局限性疾病患者中为30%。未发生术中及术后30天内并发症。约43%患者在拔除导尿管后1天内恢复尿控,3个月时75%患者实现无尿垫状态。3个月时SHIM评分与AUA-SS评分中位数较基线无显著下降。勃起功能恢复中位时间为69天,末次随访时67%患者恢复功能。6个月内2例患者(15.4%)出现生化复发。 结论:SP-TV-RARP术式安全性良好,可能促进尿控与勃起功能的早期恢复。尽管早期应用阶段肿瘤学结局可能存在不足,但功能学结果令人满意。需要进一步前瞻性研究以确认其长期肿瘤学疗效。

 

 

原文链接:

Early Continence and Erectile Function Recovery Following Transvesical Single-Port Robot-Assisted Radical Prostatectomy: Initial Single Institution Experience

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