Background/Objectives: We aim to provide pooled data on the safety and efficacy of Transvaginal Natural Orifice Transluminal Endoscopic (vNOTES) right colectomy.Methods: This systematic review was conducted according to the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The primary endpoint was the overall complication rate. Quality assessment was based on the NHLBI quality assessment tools.Results: Overall, six studies were included in this review. Overall morbidity rate was 21.9% (95% CI: 10.7–33.2%,p< 0.001), while intraoperative adverse events were noted in 19.9% (p< 0.001) of cases. Mean operation duration was 176.42 (p< 0.001) minutes. Overall hospital stay was 8.68 days (p= 0.002).Conclusions: Our analyses confirm the safety and efficacy of the approach. Given several study limitations, further large-scale and high-quality trials are required.
背景/目的：本研究旨在汇总经阴道自然腔道内镜手术（vNOTES）右半结肠切除术的安全性及有效性数据。方法：本系统综述严格遵循Cochrane手册及系统综述与荟萃分析优先报告条目（PRISMA）指南开展。主要终点指标为总体并发症发生率。质量评估采用美国国家心肺血液研究所（NHLBI）质量评估工具。结果：共纳入六项研究。总体发病率为21.9%（95%置信区间：10.7–33.2%，p<0.001），术中不良事件发生率为19.9%（p<0.001）。平均手术时长为176.42分钟（p<0.001），平均住院时间为8.68天（p=0.002）。结论：本分析证实了该术式的安全性与有效性。鉴于现有研究存在若干局限性，仍需开展大规模高质量临床试验加以验证。
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