文章：

放射治疗对眼器的影响：管理意义

The Effects of Radiation Therapy on the Ocular Apparatus: Implications for Management

原文发布日期：8 August 2025

DOI: 10.3390/cancers17162605

类型: Article

开放获取: 是

英文摘要：

Radiotherapy is utilized in the treatment of various cancers of the central nervous system and head and neck. Given the high concentration of organs-at-risk in this region, care must be exercised to minimize the dose delivered to these structures. Studies have shown that excessive radiation exposure can adversely impact the eyes, potentially resulting in the loss of their function. For instance, radiation doses greater than 50 Gy have been shown to increase the incidence of retinopathy, and radiation doses as low as 0.5 Gy have been shown to induce cataract formation. In this review, we discuss the ocular complications of radiotherapy used in the treatment of cancers of the central nervous system and head and neck. We then transition to potential strategies to spare the eyes during radiotherapy in an effort to reduce the rates and severity of ocular complications and preserve vision.

摘要翻译： 

放射疗法被广泛应用于中枢神经系统及头颈部多种癌症的治疗。鉴于该区域存在大量危及器官，必须谨慎控制对这些结构的照射剂量。研究表明，过量的辐射暴露会对眼睛产生不良影响，可能导致其功能丧失。例如，超过50 Gy的辐射剂量会增加视网膜病变的发生率，而低至0.5 Gy的辐射剂量即可诱发白内障形成。本文综述了中枢神经系统及头颈部癌症放射治疗中可能出现的眼部并发症，进而探讨在放疗过程中保护眼睛的潜在策略，以期降低眼部并发症的发生率和严重程度，保护患者视力。

原文链接：

The Effects of Radiation Therapy on the Ocular Apparatus: Implications for Management