Background: There is evidence that pancreatic cancer arises from different pre-malignant conditions, which can take decades to transform to invasive cancers. Some individuals can benefit from surveillance and early access to surgery. Patients that have disease that is detected whilst it is resectable may have the disease cured by total or partial pancreatectomy. It is already known that pancreatic cancer, whether advanced or localised, causes impairment in quality of life, and survivors of surgery can have quality of life impaired by recognised and predictable pancreatic deficiencies.Methods: A literature review of key themes affecting quality of life in pancreatic cancer are presented here.Results: The biological features of the precursors of pancreatic cancer are described, with the rationale for surveillance and effects of surgical management in different conditions.Conclusions: Surgery for pancreatic cancer carries the potential for high impact on quality of life after survivorship after initial surgical intervention. Identification of issues that affect patients are discussed with the aim of improving the quality of care for patients.
背景：有证据表明，胰腺癌起源于不同的癌前病变，这些病变可能需要数十年时间才能发展为浸润性癌症。部分人群可通过监测及早接受手术获益。对于在可切除阶段被检出疾病的患者，全胰或部分胰腺切除术可能实现疾病根治。已知胰腺癌无论处于晚期还是局部阶段，均会导致生活质量下降，而手术幸存者也可能因已知且可预见的胰腺功能缺陷而影响生活质量。 方法：本文对影响胰腺癌患者生活质量的关键主题进行了文献综述。 结果：研究描述了胰腺癌前病变的生物学特征，阐述了不同情况下进行监测的理论依据及手术治疗效果。 结论：胰腺癌手术在初次干预后，对幸存者的生活质量可能产生重大影响。本文通过探讨影响患者的相关问题，旨在提升患者的护理质量。
A Review of Quality of Life Experienced by Patients Following Surgery for Pancreatic Cancer
肿瘤(癌症)患者之家