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文章:

妇科恶性肿瘤治疗患者中压力袜预防下肢淋巴水肿的疗效:一项前瞻性随机研究

Efficacy of Compression Stockings in Prophylaxis of Lower Limb Lymphedema in Women Undergoing Treatment for Gynecological Malignancies: A Prospective Randomized Study

原文发布日期:31 July 2025

DOI: 10.3390/cancers17152530

类型: Article

开放获取: 是

 

英文摘要:

Background: Lower limb lymphedema (LLL) is a frequent complication after gynecological cancer treatment, with a significant impact on quality of life. Despite the common use of compression therapy in managing established lymphedema, its role in prevention remains insufficiently explored. Methods: In this prospective randomized study, 64 women treated for gynecological malignancies were assigned to either a compression group (CG) using medium-pressure stockings (23–32 mmHg) or a no-compression group (NCG). All participants received standard education and physical activity guidance. Limb volume, symptom burden, and quality of life were assessed over 12 months. Results: The incidence of LLL was significantly lower in the CG (3.4%) compared to the NCG (38%,p= 0.003). Compression use resulted in significant reductions in limb volume and symptom severity, as well as improved physical functioning. Compliance with compression therapy was high, and patients reported good comfort and usability. Conclusions: Medium-pressure compression stockings combined with education and physical activity are effective and well-tolerated in preventing LLL following gynecological cancer treatment.

 

摘要翻译: 

背景:下肢淋巴水肿是妇科癌症治疗后常见的并发症,严重影响患者生活质量。尽管压力治疗在已形成淋巴水肿的管理中应用广泛,但其在预防中的作用尚未得到充分探讨。方法:在这项前瞻性随机研究中,64名接受妇科恶性肿瘤治疗的女性被分配至使用中等压力袜(23-32 mmHg)的压力治疗组或无压力治疗组。所有参与者均接受标准健康教育及体力活动指导。研究对肢体体积、症状负担及生活质量进行了为期12个月的评估。结果:压力治疗组下肢淋巴水肿发生率(3.4%)显著低于无压力治疗组(38%,p=0.003)。压力治疗显著降低了肢体体积和症状严重程度,并改善了身体功能。患者对压力治疗的依从性高,且普遍反馈舒适度和实用性良好。结论:中等压力袜结合健康教育与体力活动,能有效预防妇科癌症治疗后下肢淋巴水肿的发生,且患者耐受性良好。

 

 

原文链接:

Efficacy of Compression Stockings in Prophylaxis of Lower Limb Lymphedema in Women Undergoing Treatment for Gynecological Malignancies: A Prospective Randomized Study

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