Background:Gastric neoplasms remain pathologies of the malignant spectrum with high incidence and prevalence, with their management requiring a precise histopathological characterization for optimal treatment planning.Methods:The present study is a retrospective analysis that included 67 histopathologically confirmed gastric neoplasia subjects and was performed at a single surgical center from January 2020 to December 2021. Demographics, tumor characteristics, surgical procedures, and oncologic outcomes were included, filtered, and subsequently analyzed using SPSS Statistics 29.0.Results: This study involved 67 patients (mean age 65.7 years, 56.7% men), with adenocarcinoma being the most common histologic type (91.0%) and most tumors being diagnosed directly as Stage III (40.3%). Lauren classification revealed the intestinal type as the most common (49.2%), followed by diffuse (36.1%) and mixed (14.8%). Poorly differentiated tumors (G3) accounted for 53.7% of cases. The surgical team performed curative resection in 75% (n = 50) of patients, achieving R0 margins in 88% of these cases. Subtotal gastrectomy with D2 lymphadenectomy yielded the highest curative success rate with 96.6% R0 resection. Statistically, we identified two significant correlations between age and tumor grade (rho = 0.28;p= 0.021) and between the number of lymph nodes examined and the number of lymph nodes invaded (rho = 0.65,p< 0.001). This study again revealed that adenocarcinomas showed higher rates of lymph node invasion than other tumor types (p= 0.017).Conclusions: The analysis of patients with gastric neoplasms is vital for appropriate therapeutic management. Even though the study period included a pandemic, the analysis remained a complex one with high-quality surgical outcomes, confirming the importance of maintaining oncologic standards during medical crises.
背景：胃部肿瘤作为高发病率与高患病率的恶性疾病谱系，其治疗管理需依赖精确的组织病理学特征以制定最佳治疗方案。 方法：本研究为一项回顾性分析，纳入了2020年1月至2021年12月期间在单一外科中心确诊的67例胃部肿瘤患者。研究收集了人口统计学特征、肿瘤特性、手术方式及肿瘤学结局等数据，通过SPSS Statistics 29.0软件进行筛选与分析。 结果：本研究共纳入67例患者（平均年龄65.7岁，男性占56.7%），其中腺癌为最常见的组织学类型（91.0%），多数肿瘤确诊时已处于III期（40.3%）。Lauren分型显示肠型最为常见（49.2%），其次为弥漫型（36.1%）和混合型（14.8%）。低分化肿瘤（G3）占病例总数的53.7%。手术团队对75%（n=50）的患者实施了根治性切除，其中88%的病例达到R0切缘。胃大部切除联合D2淋巴结清扫术的根治成功率最高，R0切除率达96.6%。统计学分析显示，年龄与肿瘤分级呈显著正相关（rho=0.28，p=0.021），淋巴结检出数量与淋巴结转移数量亦呈显著正相关（rho=0.65，p<0.001）。研究同时发现，腺癌的淋巴结转移率显著高于其他肿瘤类型（p=0.017）。 结论：对胃部肿瘤患者的深入分析对制定适宜治疗方案至关重要。尽管研究期间处于全球疫情阶段，本次分析仍呈现出复杂病例特征与高质量手术结局，证实了在医疗危机期间坚持肿瘤治疗标准的重要性。
肿瘤(癌症)患者之家