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文章:

胃癌肿瘤手术中辅助估计术中资源的预测因素

Predictive Factors Aiding in the Estimation of Intraoperative Resources in Gastric Cancer Oncologic Surgery

原文发布日期:18 June 2025

DOI: 10.3390/cancers17122038

类型: Article

开放获取: 是

 

英文摘要:

Background/Objectives:Operating rooms represent valuable and pivotal units of any hospital. Therefore, their management affects healthcare service delivery through rescheduling, staff shortage/overtime, cost inefficiency, and patient dissatisfaction, among others. To optimize scheduling, we aim to assess preoperative evaluation criteria that influence the prediction of surgery duration for gastric cancer (GC) patients. In GC, radical surgery with curative intent is the ideal treatment. Nevertheless, the intervention sometimes must be palliative if the patient’s status and tumor staging prove too advanced.Methods:A 6-year retrospective cohort study was performed in a tertiary care hospital, including all cases diagnosed with GC (ICD-10 code C16), confirmed through histopathology, and undergoing surgical treatment (N = 108).Results:The results of our study confirm male predominance (63.89%) among GC surgery candidates while bringing new perspectives on patient evaluation criteria and choice of surgical intervention (curative—Group 1, palliative—Group 2). Surgery duration, including anesthesiology (175.19 [95% CI (157.60–192.77)] min), shows a direct correlation with the number of lymph nodes dissected (Surgical duration [min] = 10.67 × No. of lymph nodes removed − 32.25). Interestingly, the aggressiveness of the tumor based on histological grade (highly differentiated being generally less aggressive than poorly differentiated) shows differential correlation with surgery duration among curative and palliative surgery candidates. Similarly, TNM staging indicates the need for a longer surgical duration (pTNM stage IIA, IIB, and IIIA) for curative interventions in patients with less advanced stages, as opposed to shorter surgery duration for palliative interventions (pTNM stage IIIC and IV).Conclusions:The study quantitatively presents the resources needed for the optimal surgical treatment of different groups of GC patients, as the disease coding systems in use regard the treatment of each pathology as “standard” in terms of patient management. The results obtained are anchored in the global perspectives of surgical outcomes and aim to improve the management of operating room scheduling, staff, and resources.

 

摘要翻译: 

背景/目的:手术室是医院中至关重要且核心的单元。因此,其管理通过重新排程、人员短缺/加班、成本效率低下及患者不满等因素影响医疗服务提供。为优化排程,本研究旨在评估影响胃癌患者手术时长预测的术前评估标准。对于胃癌,以根治为目的的手术是理想治疗方案。然而,若患者状况和肿瘤分期过于晚期,有时则需采取姑息性干预。 方法:在一家三级医院开展为期6年的回顾性队列研究,纳入所有经组织病理学确诊为胃癌(ICD-10编码C16)并接受手术治疗的患者(N=108)。 结果:研究结果证实胃癌手术患者以男性为主(63.89%),同时在患者评估标准和手术干预选择(根治组——第1组,姑息组——第2组)方面提出了新见解。包含麻醉时间在内的手术时长(175.19[95%CI(157.60–192.77)]分钟)与清扫淋巴结数量呈直接正相关(手术时长[分钟]=10.67×淋巴结清扫数量−32.25)。值得注意的是,基于组织学分级的肿瘤侵袭性(高分化通常较低分化侵袭性弱)在根治组与姑息组患者中与手术时长的相关性呈现差异。同样,TNM分期显示:对于分期较早的患者(pTNM分期IIA、IIB和IIIA),根治性干预需要更长手术时间;而姑息性干预(pTNM分期IIIC和IV)则手术时间较短。 结论:本研究定量呈现了不同组别胃癌患者接受优化手术治疗所需的资源,因为现行疾病编码系统在患者管理层面将每种病理的治疗视为"标准"。研究结果立足于手术结局的全球视野,旨在改善手术室排程、人员及资源管理。

 

 

原文链接:

Predictive Factors Aiding in the Estimation of Intraoperative Resources in Gastric Cancer Oncologic Surgery

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