Early detection of cancer is crucial for improving patient outcomes. Traditional modalities such as mammography and low-dose computed tomography are effective but exhibit inherent limitations, including radiation exposure and accessibility challenges. This review explores innovative, non-invasive cancer screening methods, focusing on liquid biopsy and volatile organic compound (VOC)-based detection platforms. Liquid biopsy analyzes circulating tumor DNA and other biomarkers in bodily fluids, offering potential for early detection and monitoring of treatment response. VOC-based detection leverages unique metabolic signatures emitted by cancer cells, detectable in exhaled breath or other bodily emissions, providing a rapid and patient-friendly screening option. We provide a comprehensive overview of these advanced multi-cancer detection techniques to enhance diagnostic accuracy, accessibility, and patient adherence, and ultimately enhance survival rates and patient outcomes.
癌症的早期检测对于改善患者预后至关重要。传统筛查手段如乳腺X线摄影和低剂量计算机断层扫描虽具成效，但存在辐射暴露和可及性受限等固有缺陷。本综述探讨创新的无创癌症筛查方法，重点关注液体活检与基于挥发性有机化合物（VOC）的检测平台。液体活检通过分析体液中循环肿瘤DNA等生物标志物，为早期发现和治疗反应监测提供可能；VOC检测技术则利用癌细胞释放的特异性代谢特征，通过呼出气或其他体液排放物实现快速、便捷的筛查。本文系统综述这些先进的多癌种检测技术，旨在提升诊断准确性、筛查可及性与患者依从性，最终提高生存率并改善临床结局。
肿瘤(癌症)患者之家