文章：

Overall Survival of Hungarian Cancer Patients Diagnosed Between 2011 and 2019, Based on the Health Insurance Fund Database

原文发布日期：15 May 2025

DOI: 10.3390/cancers17101670

类型: Article

开放获取: 是

英文摘要：

Background:Assessing cancer survival trends is crucial for monitoring progress in cancer management and prevention. As part of the broader HUN-CANCER EPI study, this analysis examined overall survival (OS) in the Hungarian cancer population between 2011 and 2019.Methods:Using data extracted from the Hungarian National Health Insurance Fund (NHIF) database, short- and long-term OS were estimated for various cancer types according to age, sex, and diagnostic period using Kaplan–Meier analysis. The study also identified cancer types with significant early mortality following diagnosis.Results:From 2011 to 2019, a total of 528,808 patients were diagnosed with cancer. During the 2015–2019 diagnostic period, the lowest 5-year OS rates were observed for esophageal (7.0%), pancreatic (10.7%), liver (12.5%), gallbladder (13.9%), and lung cancer (18.4%). Conversely, tumor types with better OS included testicular cancer (91.6%), thyroid cancer (89.0%), Hodgkin’s lymphoma (84.0%), melanoma (78.6%), and breast cancer (74.1%). A notable proportion of deaths occurred within 2 months of diagnosis for liver (33.2%), pancreatic (27.9%), and gallbladder cancer (29.0%). Significant early mortality within 6 months post-diagnosis was also noted for esophageal (51.3%), stomach (42.9%), and lung cancer (41.7%).Conclusions:The HUN-CANCER EPI study conducted between 2011 and 2019 provides valuable insights into cancer survival patterns in Hungary, emphasizing the importance of early detection and targeted interventions to improve patient outcomes.

摘要翻译： 

背景：评估癌症生存趋势对于监测癌症管理和预防进展至关重要。作为HUN-CANCER EPI研究的一部分，本分析考察了2011年至2019年间匈牙利癌症人群的总生存期（OS）。 方法：通过从匈牙利国家健康保险基金（NHIF）数据库中提取数据，采用Kaplan-Meier分析法，根据年龄、性别和诊断时期对不同癌症类型的短期及长期OS进行估算。研究还识别了诊断后早期死亡率显著的癌症类型。 结果：2011年至2019年间，共有528,808名患者被诊断为癌症。在2015-2019年诊断期间，5年OS最低的癌症类型包括食管癌（7.0%）、胰腺癌（10.7%）、肝癌（12.5%）、胆囊癌（13.9%）和肺癌（18.4%）。相反，OS较好的肿瘤类型包括睾丸癌（91.6%）、甲状腺癌（89.0%）、霍奇金淋巴瘤（84.0%）、黑色素瘤（78.6%）和乳腺癌（74.1%）。肝癌（33.2%）、胰腺癌（27.9%）和胆囊癌（29.0%）在诊断后2个月内死亡的比例较高。食管癌（51.3%）、胃癌（42.9%）和肺癌（41.7%）在诊断后6个月内也表现出显著的早期死亡率。 结论：2011年至2019年间进行的HUN-CANCER EPI研究为匈牙利癌症生存模式提供了重要见解，强调了早期检测和针对性干预对改善患者预后的重要性。

原文链接：

Overall Survival of Hungarian Cancer Patients Diagnosed Between 2011 and 2019, Based on the Health Insurance Fund Database