文章：

评估胶质瘤治疗效果的临床结局评估工具

Clinical Outcome Assessment Tools for Evaluating the Management of Gliomas

原文发布日期：14 May 2025

DOI: 10.3390/cancers17101659

类型: Article

开放获取: 是

英文摘要：

In recent times, a greater emphasis has been placed on framing patient clinical assessments and QOL as both endpoints and prognostic factors for neuro-oncological care. However, there is currently a lack of consensus on the most effective metrics and instruments for use in patients with primary brain tumors. Due to the heterogeneity in clinical characteristics, histological classification, anatomical location, and available treatment modalities for glioma, quantifying patient clinical condition and QOL within this unique population is particularly challenging. In this paper, we comprehensively review the available literature on the use of clinical assessment tools in glioma patients, highlighting the strengths and limitations of prominent instruments. We demonstrate that clinical outcome assessment (COA) instruments provide valuable and complementary insights into the physical, psychological, and spiritual well-being of glioma patients.

摘要翻译： 

近年来，神经肿瘤诊疗领域日益重视将患者临床评估与生活质量作为治疗终点和预后因素。然而目前针对原发性脑肿瘤患者，尚缺乏公认的有效评估指标与测量工具。由于胶质瘤在临床特征、组织学分类、解剖位置及可用治疗方式等方面存在高度异质性，对这一特殊人群的临床状况与生活质量进行量化评估尤为困难。本文系统综述了胶质瘤患者临床评估工具的相关文献，重点分析了主流测量工具的优势与局限。研究表明，临床结局评估工具能够为胶质瘤患者的生理、心理及精神健康状况提供具有重要价值且互为补充的评估视角。

原文链接：

Clinical Outcome Assessment Tools for Evaluating the Management of Gliomas