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文章:

长期乳腺癌幸存者情绪功能状况:一项关于其影响及关键预测因素的横断面研究

Emotional Functioning in Long-Term Breast Cancer Survivors: A Cross-Sectional Study on Its Influence and Key Predictors

原文发布日期:6 May 2025

DOI: 10.3390/cancers17091574

类型: Article

开放获取: 是

 

英文摘要:

Background/Objectives: This study aimed to analyze the relationship between emotional functioning and health status in long-term breast cancer survivors (LTBCSs). Additionally, it sought to identify factors that could influence emotional functioning in this population at least five years after cancer diagnosis.Methods: This cross-sectional observational study included 80 LTBCSs, classified into the following two groups, according to their emotional functioning: those experiencing psychological distress (≤90) and those with satisfactory psychological well-being (≥91). The study examined various factors at least five years post-diagnosis, including sociodemographic and clinical characteristics, health-related quality of life (HRQoL), mood state, self-perceived physical fitness, physical activity (PA) level, pain, and cancer-related fatigue (CRF). ANOVA, Mann–Whitney U, and Chi-square tests were conducted, along with correlation and multiple regression analysis. Effect sizes were calculated using Cohen’sd.Results: Among the 80 LTBCSs, 47.50% reported psychological distress, while 52.50% maintained satisfactory psychological well-being. Participants in the psychological distress group exhibited significantly poorer HRQoL, lower mood, and reduced self-perceived physical fitness, as well as higher levels of physical inactivity, pain, and CRF (p< 0.05). Regression analysis revealed that “role functioning” (β = 0.59;p< 0.01), “cognitive functioning” (β = 0.26;p< 0.01), “self-perceived physical fitness” (β = 0.20;p= 0.02), and “sadness–depression” (β = 0.18;p= 0.04) were significant predictors of emotional functioning (r2adjusted = 0.642).Conclusions: These results emphasize the association between emotional functioning and health status in LTBCSs. Role functioning, cognitive functioning, self-perceived physical fitness, and mood state were identified as relevant factors influencing emotional well-being in this population. Considering these relationships, integrating psychological and physical assessments into survivorship care could support the early detection of at-risk individuals. This approach could also guide interventions to improve their long-term well-being and HRQoL.

 

摘要翻译: 

**背景/目的:** 本研究旨在分析长期乳腺癌生存者(LTBCSs)的情绪功能与健康状况之间的关系。此外,本研究试图识别在癌症诊断至少五年后,可能影响该人群情绪功能的因素。 **方法:** 这项横断面观察性研究纳入了80名LTBCSs,根据其情绪功能分为以下两组:经历心理困扰组(≤90分)和心理幸福感良好组(≥91分)。研究在诊断后至少五年时,考察了多种因素,包括社会人口学和临床特征、健康相关生活质量(HRQoL)、情绪状态、自我感知体能、体力活动(PA)水平、疼痛以及癌症相关疲劳(CRF)。研究进行了方差分析、曼-惠特尼U检验和卡方检验,以及相关性和多元回归分析。效应量使用Cohen's d计算。 **结果:** 在80名LTBCSs中,47.50%报告存在心理困扰,而52.50%保持心理幸福感良好。心理困扰组的参与者在HRQoL、情绪状态和自我感知体能方面显著更差,同时体力活动不足、疼痛和CRF水平更高(p < 0.05)。回归分析显示,"角色功能"(β = 0.59; p < 0.01)、"认知功能"(β = 0.26; p < 0.01)、"自我感知体能"(β = 0.20; p = 0.02)和"悲伤-抑郁"情绪(β = 0.18; p = 0.04)是情绪功能的显著预测因子(调整后r² = 0.642)。 **结论:** 这些结果强调了LTBCSs中情绪功能与健康状况之间的关联。角色功能、认知功能、自我感知体能和情绪状态被确定为影响该人群情绪幸福感的相关因素。考虑到这些关系,将心理和身体评估整合到生存期照护中,可能有助于早期识别高危个体。这种方法也可指导干预措施,以改善其长期幸福感和HRQoL。

 

原文链接:

Emotional Functioning in Long-Term Breast Cancer Survivors: A Cross-Sectional Study on Its Influence and Key Predictors

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