(1) Background: Implantable port catheters are vital for cancer treatment, but complications such as infections and mechanical failures pose challenges. Lymphoma and leukemia patients’ unique cellular abnormalities may influence these risks. This study aimed to determine whether the underlying disease or varying degrees of cytopenia increase the risk of unplanned early port removal. (2) Methods: We conducted a single institution retrospective study that included 368 patients with lymphoma or leukemia who received implantable venous access ports between January 2015 and December 2022. Propensity score matching was employed to compare patients with and without early removals. (3) Results: Univariate analysis revealed statistically significant differences between early and non-early port removal for cancer, hemoglobin, and PG-SGA scores. Cox proportional hazard analysis demonstrated that leukemia patients exhibited a 4.5 times higher risk for unplanned early catheter removal than lymphoma patients did (HR 4.589, 95% CI 1.377–15.299,p= 0.013), while patients with normal nutrition, based on the PS-SGA, demonstrated a 75% lower risk of unplanned early catheter removal than those with any degree of malnutrition did (HR 0.258, 95% CI 0.116–0575,p< 0.001). Unplanned early catheter removal negatively impacted patient survival. (4) Conclusions: The type of cancer, rather than individual cytopenias, is an independent factor influencing clinical outcomes in lymphoma and leukemia patients.
（1）背景：植入式输液港是癌症治疗的关键装置，但感染和机械故障等并发症带来临床挑战。淋巴瘤和白血病患者特有的细胞异常可能影响相关风险。本研究旨在探讨原发疾病或不同程度的血细胞减少是否会增加非计划性早期输液港移除的风险。（2）方法：我们开展了一项单中心回顾性研究，纳入2015年1月至2022年12月期间接受植入式静脉输液港的368例淋巴瘤或白血病患者。采用倾向评分匹配法比较早期移除组与非早期移除组患者。（3）结果：单因素分析显示，在癌症类型、血红蛋白水平和PG-SGA评分方面，早期与非早期输液港移除组存在统计学显著差异。Cox比例风险模型分析表明：白血病患者非计划性早期导管移除风险是淋巴瘤患者的4.5倍（HR 4.589，95% CI 1.377–15.299，p=0.013）；而根据PS-SGA评估营养状况正常的患者，其非计划性早期导管移除风险比任何程度营养不良患者降低75%（HR 0.258，95% CI 0.116–0.575，p<0.001）。非计划性早期导管移除对患者生存率产生负面影响。（4）结论：在淋巴瘤和白血病患者中，癌症类型（而非个体血细胞减少状况）是影响临床结局的独立因素。
肿瘤(癌症)患者之家