Background/Objectives: Dental caries is believed to be one of the most frequent dental long-term adverse effects of anticancer therapy. It may occur due to numerous chemotherapy-dependent oral symptoms or due to the possible neglection of oral care because of parental involvement in the monitoring of other long-term effects of the therapy. This study aimed to determine the incidence of dental caries and the impact of other risk factors in cancer survivors and age-matched controls. Methods: This cross-sectional study was conducted on 40 cancer survivors and 80 peers divided into three age groups. Indices such as dmft/s, DMFT/S, ft/s, FT/S, Plaque Index (PI), and Gingival Index (GI) were calculated to compare the study participants. The sum of dmft and DMFT was used to assess the possible impact of socioeconomic, oral hygiene, and dietary factors. Results: Caries frequency was found to be lower in cancer survivors (92.50%) than in controls (97.50%). No statistically significant differences were found between the study groups within all the caries indices examined. Strong positive correlations with PI and cariogenic diet in the youngest survivors and with PI in middle-aged survivors were observed. Strong negative correlations in middle-aged children were noticed in terms of father’s education in survivors and mother’s education in controls. Conclusions: The study findings suggest that there is no relationship between chemotherapy and dental caries in long-term cancer survivors. Careful dental care still remains a major contributor to maintaining oral health.
背景/目的：龋齿被认为是抗癌治疗中最常见的长期口腔不良影响之一。其发生可能与化疗相关的多种口腔症状有关，也可能由于家长专注于监测治疗的其他长期副作用而忽视了口腔护理。本研究旨在确定癌症幸存者与年龄匹配对照组中龋齿的发生率及其他风险因素的影响。方法：这项横断面研究纳入了40名癌症幸存者和80名同龄人，并将其分为三个年龄组。通过计算dmft/s、DMFT/S、ft/s、FT/S、菌斑指数（PI）和牙龈指数（GI）等指标对参与者进行比较。采用dmft与DMFT之和评估社会经济状况、口腔卫生及饮食因素可能产生的影响。结果：癌症幸存者的龋齿发生率（92.50%）低于对照组（97.50%）。在所有检测的龋齿指数中，研究组间均未发现具有统计学意义的差异。在年幼幸存者中观察到菌斑指数与致龋饮食呈强正相关，在中年幸存者中观察到与菌斑指数呈强正相关。在中年儿童中，幸存者父亲受教育程度与对照组母亲受教育程度均呈现强负相关。结论：研究结果表明，长期癌症幸存者的化疗与龋齿之间不存在关联。精心的口腔护理仍是维持口腔健康的重要因素。
Risk Factors and Dental Caries Incidence in Childhood Cancer Survivors
肿瘤(癌症)患者之家