Gastrointestinal cancers, especially colorectal cancer, represent a major health care issue. According to the data, the incidence of these cancers exceeds 50/100,000, mainly in high-income countries. Risk factors for the disease include genetic factors (i.e., Lynch syndrome) and lifestyle factors, e.g., overweight and obesity, smoking tobacco products, low-fiber diet, and low physical activity. When diagnosed early, gastrointestinal cancers can, in most cases, be effectively treated. This review focuses on the presentation of research in the area of screening and its results. It provides insights into current trends in research on methods of early cancer detection and improving screening reporting. Differing levels of screening reporting are one of the main challenges faced by researchers in this field. Research on this issue should be conducted in parallel with research on methods of early diagnosis. Finally, the development of diagnostic methods and communication with patients are important elements of public health.
胃肠道癌症,尤其是结直肠癌,已成为一项重大的公共卫生问题。数据显示,此类癌症的发病率超过50/10万,主要集中于高收入国家。疾病风险因素包括遗传因素(如林奇综合征)及生活方式因素,例如超重与肥胖、吸烟、低纤维饮食和缺乏体力活动。若早期确诊,大多数胃肠道癌症可获得有效治疗。本综述聚焦于筛查领域的研究进展及其成果,深入探讨当前癌症早期检测方法与筛查报告改进的研究趋势。筛查报告质量参差不齐是该领域研究者面临的主要挑战之一,相关研究应与早期诊断方法探索同步推进。最后,诊断方法的完善及医患沟通的优化是公共卫生体系的重要环节。
Screening in Gastrointestinal Malignancies—Recent Trials and Advancements