文章：

内镜超声引导下胃肠道吻合术：一项多中心经验研究

Endoscopic Ultrasound-Guided Anastomoses of the Gastrointestinal Tract: A Multicentric Experience

原文发布日期：6 March 2025

DOI: 10.3390/cancers17050910

类型: Article

开放获取: 是

英文摘要：

This multicenter retrospective study included patients undergoing EUS-guided GI anastomoses from 2016 to 2023. Indications for EUS-guided anastomosis were GOO, ALS or patients with altered anatomy needing endoscopic interventions. The primary outcome was technical success, while secondary outcomes included clinical success, safety, lumen-apposing metal stent (LAMS) patency, and the need for reinterventions. A total of 216 patients (mean age 64.5 [±13.94] years; 49.1% males) were included. In total, 149 cases (69%) were GOO, 44 (20.4%) cases were bilioenteric anastomotic strictures or lithiasis in altered anatomy, 14 cases (6.5%) were ALS, and 9 patients (4.2%) were for ERCP in altered anatomy after EUS-GG. Overall, EUS-GE was performed in 181 patients (83.8%), EUS-JJ in 44 cases (20.4%), and EUS-GG in 10 (4.6%). Technical success was 94.91%, and clinical success was 93.66%. The adverse event (AE) rate was 11.1%. The reintervention rate was 7.69%. The median follow-up was 85 days. In conclusions, EUS-guided GI anastomoses are technically feasible and safe in both malignant and benign diseases.

摘要翻译： 

这项多中心回顾性研究纳入了2016年至2023年间接受超声内镜引导下胃肠吻合术的患者。超声内镜引导吻合的适应症包括胃流出道梗阻、胆管空肠吻合口狭窄或因解剖结构改变需行内镜干预的患者。主要结局指标为技术成功率，次要结局指标包括临床成功率、安全性、管腔贴合金属支架通畅度以及再干预需求。研究共纳入216例患者（平均年龄64.5[±13.94]岁；男性占49.1%）。其中胃流出道梗阻149例（69%），解剖结构改变后的胆肠吻合口狭窄或结石44例（20.4%），胆管空肠吻合口狭窄14例（6.5%），超声内镜引导胃胃吻合术后因解剖结构改变需行ERCP者9例（4.2%）。总体而言，实施超声内镜引导胃空肠吻合术181例（83.8%），超声内镜引导空肠空肠吻合术44例（20.4%），超声内镜引导胃胃吻合术10例（4.6%）。技术成功率为94.91%，临床成功率为93.66%。不良事件发生率为11.1%，再干预率为7.69%。中位随访时间为85天。结论表明，超声内镜引导胃肠吻合术在良恶性疾病中均具有技术可行性和安全性。

原文链接：

Endoscopic Ultrasound-Guided Anastomoses of the Gastrointestinal Tract: A Multicentric Experience