Objectives: (i) To evaluate the possible exposure of newly diagnosed lung cancer patients to selected lifestyle, environmental, occupational, and dietary risk factors and (ii) to assess the differences in exposures of small-cell (SCLC) and non-small-cell (NSCLC) lung cancer patients to those risk factors. Methods: In this study, 205 newly diagnosed patients with IIIB/IV stage of either SCLC or NSCLC (111 men vs. 94 women) from Vojvodina, Serbia, were surveyed for selected demographic characteristics, dietary and lifestyle habits, and environmental factors. Results: Most patients were long-term heavy smokers. The body mass index values of SCLC patients were higher than those of NSCLC patients. Women reported higher stress levels compared to men. Women diagnosed with lung adenocarcinoma were more often exposed to traffic pollution compared to men. Individual indoor coal combustion systems were more often used by SCLC patients of both sexes compared to other cancer types. Men were more frequent consumers of canned foods, which are potential sources of endocrine disruptors. Occupational exposure to lung cancer risk factors, in addition to tobacco smoking, may be crucial in lung cancer development with specific occupations. Conclusions: Further research on environmental and occupational risk factors for lung cancer is urgent in order to unveil the etiopathogenesis of specific lung cancer types.
目的：(i) 评估新诊断肺癌患者可能接触的特定生活方式、环境、职业及饮食风险因素；(ii) 分析小细胞肺癌与非小细胞肺癌患者在这些风险因素暴露水平上的差异。方法：本研究对来自塞尔维亚伏伊伏丁那地区的205例新诊断IIIB/IV期小细胞肺癌或非小细胞肺癌患者（男性111例，女性94例）进行调查，收集其人口学特征、饮食生活习惯及环境暴露数据。结果：多数患者为长期重度吸烟者。小细胞肺癌患者的体重指数值高于非小细胞肺癌患者。女性自述压力水平高于男性。肺腺癌女性患者比男性更频繁暴露于交通污染环境。与其他肺癌类型相比，两性小细胞肺癌患者更常使用个体燃煤供暖系统。男性更频繁食用罐头食品（该类食品是潜在的内分泌干扰物来源）。除吸烟外，特定职业人群的职业性肺癌风险因素暴露可能在肺癌发生发展中起关键作用。结论：为揭示特定肺癌类型的病因发病机制，亟需深入开展肺癌环境与职业风险因素的进一步研究。
肿瘤(癌症)患者之家