Background/Objectives:Basal cell carcinoma (BCC) is the most common malignancy, characterised by local invasiveness and the potential for tissue destruction. Diagnosing BCC can be challenging, particularly for less experienced dermatologists. Line-field confocal optical coherence tomography (LC-OCT), a new noninvasive optical technique, has become increasingly useful in clinical practice, allowing in vivo imaging at cellular resolution. This study aimed to evaluate the impact of a 1 h structured training session on the ability of dermatology residents to diagnose BCC using LC-OCT.Methods:Eight dermatology residents with different levels of LC-OCT experience (no experienced and low experience in LC-OCT) participated alongside an expert dermatologist as a benchmark. Overall, participants evaluated 40 histopathologically confirmed lesions (20 BCC, 20 non-BCC) before and after training, with and without the inclusion of dermoscopic images.Results:We observed a significant improvement in diagnostic accuracy post-training, especially among inexperienced users, with a 20% reduction in false negatives and a 35% reduction in false positives. When the dermoscopic images were included, further improvements were noted, with the accuracy increasing by an additional 5%. The overall diagnostic rate for inexperienced readers increased from 48% to 76% after training and to 81% with the addition of dermoscopic images in the course.Conclusions:Our study highlights the effectiveness of short, targeted training in enhancing the diagnostic utility of LC-OCT, emphasising its potential for broader clinical adoption to improve BCC detection.
背景/目的：基底细胞癌（BCC）是最常见的皮肤恶性肿瘤，以局部侵袭性和组织破坏潜力为特征。BCC的诊断具有挑战性，尤其对于经验较少的皮肤科医生而言。线场共聚焦光学相干断层扫描（LC-OCT）作为一种新型无创光学技术，在临床实践中日益显示出其应用价值，能够实现细胞级分辨率的活体成像。本研究旨在评估为期1小时的结构化培训课程对皮肤科住院医师使用LC-OCT诊断BCC能力的影响。 方法：八名具有不同LC-OCT经验水平（无经验或低经验）的皮肤科住院医师参与研究，并以一名皮肤科专家作为基准。参与者分别在培训前后，结合或不结合皮肤镜图像，对40个经组织病理学确诊的皮损（20个BCC，20个非BCC）进行了评估。 结果：我们观察到培训后诊断准确性显著提高，尤其是在无经验使用者中，假阴性率降低了20%，假阳性率降低了35%。当结合皮肤镜图像时，诊断准确性得到进一步提升，准确率额外增加了5%。无经验阅片者的总体诊断率在培训后从48%提高至76%，而在培训过程中结合皮肤镜图像后，诊断率进一步提高至81%。 结论：我们的研究强调了短期针对性培训在提升LC-OCT诊断效能方面的有效性，并凸显了其在更广泛临床应用中改善BCC检测的潜力。
肿瘤(癌症)患者之家