Background/Objectives: Semen cryopreservation has been widely used in recent decades, mainly in patients with male factor infertility (MFI) and patients with cancer (to preserve their fertility potential before undergoing gonadotoxic treatments, such as chemotherapy or radiotherapy).Methods: we evaluated the temporal trend and the existence of factors determining the usage of cryopreserved semen (in order, for instance, to conceive using assisted reproduction techniques (ARTs)). We evaluated 7044 patients who cryopreserved since 1991, evaluating clinical information such as the diagnosis, age, the method with which the collection took place and the number of pick-ups for use in ART.Results: The mean age of the patients was 33.12 ± 8.41 years. The most common cancers were testicular (1758/3262) and hematological cancers (942/3262). Patients who underwent cryopreservation for MFI picked up their samples much more than neoplastic patients (42.15% vs. 8.55%). Patients 35–40 years old picked up their samples more frequently when compared with other age groups. Moreover, we found several data regarding the sub-types of cancers and the methods of semen collection.Conclusions: According to our results, the indication for semen cryopreservation, age and the method of collection might represent a simple way to predict the future use of semen for ART.
背景/目的：近几十年来，精子冷冻保存技术已得到广泛应用，主要应用于男性因素不育症患者及癌症患者（旨在接受化疗或放疗等性腺毒性治疗前保存其生育潜能）。方法：本研究评估了冷冻精子使用的时间趋势及其影响因素（例如为通过辅助生殖技术实现妊娠而使用冷冻精子）。我们回顾了自1991年以来接受冷冻保存的7044例患者，评估了包括诊断类型、年龄、取精方式及用于辅助生殖技术的取用次数等临床信息。结果：患者平均年龄为33.12±8.41岁。最常见的癌症类型为睾丸癌（1758/3262）和血液系统恶性肿瘤（942/3262）。因男性因素不育进行冷冻保存的患者取用样本的比例显著高于肿瘤患者（42.15%对比8.55%）。35-40岁年龄组患者相较于其他年龄组更频繁地取用样本。此外，我们还获得了关于癌症亚型及取精方式的多项数据。结论：研究结果表明，精子冷冻保存的适应证、患者年龄及取精方式可作为预测未来辅助生殖技术中精子使用情况的简易评估指标。
肿瘤(癌症)患者之家