文章：

炎症性肠病相关结直肠肿瘤

Colorectal Neoplasia in Inflammatory Bowel Disease

原文发布日期：16 February 2025

DOI: 10.3390/cancers17040665

类型: Article

开放获取: 是

英文摘要：

Patients with inflammatory bowel disease (IBD), including ulcerative colitis and colonic Crohn’s disease, are at an increased risk of developing colonic dysplasia and neoplasia. Multiple risk factors have been identified that increase the risk of colonic neoplasia in IBD, including but not limited to underlying disease extent, severity, duration, and concomitant primary sclerosing cholangitis. The overall risk of colonic neoplasia in IBD is decreasing but surveillance is still warranted in patients with high-risk features. In this review, we will discuss the epidemiology, pathogenesis, risk factors, approach to surveillance, and management of colonic neoplasia in IBD.

摘要翻译： 

炎症性肠病（IBD）患者，包括溃疡性结肠炎和结肠型克罗恩病，其发生结肠异型增生和肿瘤的风险显著增加。目前已明确多种增加IBD患者结肠肿瘤风险的因素，包括但不限于基础病变范围、严重程度、病程以及合并原发性硬化性胆管炎。尽管IBD患者结肠肿瘤的总体风险呈下降趋势，但对于具有高危特征的患者仍需进行监测。本综述将探讨IBD相关结肠肿瘤的流行病学、发病机制、危险因素、监测策略及临床管理。

原文链接：

Colorectal Neoplasia in Inflammatory Bowel Disease