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文章:

在ESGO认证中心对重度肥胖虚弱患者进行机器人手术治疗非典型子宫内膜增生及子宫内膜癌的倾向性匹配分析

Robotic Surgery in Severely Obese Frail Patients for the Treatment of Atypical Endometrial Hyperplasia and Endometrial Cancer: A Propensity-Match Analysis at an ESGO-Accredited Center

原文发布日期:1 February 2025

DOI: 10.3390/cancers17030482

类型: Article

开放获取: 是

 

英文摘要:

Background and Objectives: Robotic-assisted laparoscopy (RS) has been widely adopted for the management of endometrial cancer (EC) due to favorable perioperative outcomes, especially in the context of obesity, which is an established risk factor for EC. This study retrospectively evaluated the perioperative outcomes of RS versus conventional laparoscopy (LS) in treating EC and atypical endometrial hyperplasia (AH). Methods: Between November 2021 and October 2023, 138 patients with AH or EC underwent surgery at the Clinic of Obstetric and Gynecological—Azienda Sanitaria Universitaria Friuli Centrale, Udine. All patients had total hysterectomy with bilateral salpingo-oophorectomy, with or without lymphadenectomy or sentinel lymph node biopsy. The study included 62 patients treated with LS and 62 with RS. Results: The median BMI was higher in the RS group (35.5 vs. 24 kg/m2,p= 0.001). There was no significant difference in operative time between the laparoscopic group and the robotic console time (median 130 vs. 130 min,p= 0.131). No significant differences were found in terms of blood loss, conversion to laparotomy, intraoperative complications, hospital stay, or early postoperative complications between the two groups. Conclusions: Our data confirm the feasibility of robotic surgery in obese patients, allowing surgical results comparable to those of laparoscopy in normal-weight patients.

 

摘要翻译: 

背景与目的:机器人辅助腹腔镜手术(RS)因其良好的围手术期结果,尤其是在肥胖这一子宫内膜癌(EC)明确风险因素的背景下,已被广泛应用于子宫内膜癌的治疗。本研究回顾性评估了RS与传统腹腔镜手术(LS)在治疗子宫内膜癌及非典型子宫内膜增生(AH)中的围手术期结果。方法:2021年11月至2023年10月期间,138名AH或EC患者在乌迪内的Friuli Centrale大学附属医院妇产科诊所接受了手术。所有患者均接受了全子宫切除术及双侧输卵管卵巢切除术,部分患者同时进行了淋巴结清扫术或前哨淋巴结活检。研究纳入了62名接受LS治疗的患者和62名接受RS治疗的患者。结果:RS组的中位体重指数(BMI)较高(35.5 vs. 24 kg/m²,p=0.001)。腹腔镜组与机器人控制台操作时间之间无显著差异(中位时间均为130分钟,p=0.131)。两组在失血量、中转开腹率、术中并发症、住院时间或术后早期并发症方面均未发现显著差异。结论:我们的数据证实了机器人手术在肥胖患者中的可行性,其手术结果可与正常体重患者的腹腔镜手术效果相媲美。

 

原文链接:

Robotic Surgery in Severely Obese Frail Patients for the Treatment of Atypical Endometrial Hyperplasia and Endometrial Cancer: A Propensity-Match Analysis at an ESGO-Accredited Center

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