Lung cancer, the second most common malignancy in both men and women, poses a significant health burden. Early diagnosis remains pivotal in reducing lung cancer mortality. Given the escalating number of computed tomography (CT) examinations in both outpatient and inpatient settings, radiologists play a crucial role in identifying early-stage pulmonary cancers, particularly non-nodular cancers. Screening programs have been instituted to achieve this goal, and they have raised attention within the scientific community to lung cancers associated with cystic airspaces. These cancers, although they have been known for at least a decade, remain understudied. Limited investigations with small sample sizes have estimated their prevalence and explored their radiological and pathological features. Lung cancers associated with cystic airspaces exhibit varying complexities within their cystic components and demonstrate suspicious changes over time. Adenocarcinoma is the predominant histological type, often with a peripheral location. Differential diagnosis on CT scans includes inflammatory processes or emphysema-related changes. Unfortunately, prospective studies specifically analyzing the prevalence of cystic airspace-associated lung cancers are lacking. However, it is estimated that they constitute approximately one-fourth of delayed radiological diagnoses. Increased awareness among radiologists could lead to more timely identification and potentially reduce lung cancer mortality in a cost-effective manner.
肺癌作为男性和女性中第二常见的恶性肿瘤，构成了重大的健康负担。早期诊断对于降低肺癌死亡率至关重要。随着门诊和住院患者计算机断层扫描（CT）检查数量的不断增加，放射科医生在识别早期肺癌，特别是非结节性肺癌方面发挥着关键作用。为此已建立筛查项目，这些项目使科学界对囊性气腔相关肺癌的关注度日益提升。这类肺癌虽已被认识至少十年，但相关研究仍显不足。现有少量小样本研究对其患病率进行了估算，并探讨了其影像学与病理学特征。囊性气腔相关肺癌的囊性成分具有不同的复杂程度，并随时间推移呈现可疑变化。腺癌是主要的组织学类型，常位于肺外周。CT鉴别诊断需考虑炎症性病变或肺气肿相关改变。遗憾的是，目前尚缺乏专门分析囊性气腔相关肺癌患病率的前瞻性研究。据估计，这类肺癌约占影像学延迟诊断病例的四分之一。提高放射科医生对该疾病的认识，有望以更具成本效益的方式实现更及时的识别，从而可能降低肺癌死亡率。
肿瘤(癌症)患者之家