Background: This study evaluates the impact of three-dimensional (3D) printing-guided maxillectomy compared with conventional maxillectomy on surgical precision and oncological outcomes in patients with head and neck cancer. Materials and Methods: A retrospective analysis was conducted on 42 patients undergoing maxillectomy (16 in a 3D printing-guided group and 26 in a conventional group). Patient demographics, tumor characteristics, and outcomes were compared. Survival outcomes were analyzed using the Kaplan–Meier method. Results: The 3D printing group showed higher rates of negative resection margins (81.3% vs. 76.9%) compared with the conventional group and a trend toward improved 5-year local recurrence-free survival (87.5% vs. 58.7%, respectively) and overall survival (84.4% vs. 70.1%, respectively). However, the differences were not statistically significant. Conclusions: Maxillectomy guided by 3D printing may offer enhanced surgical precision and improved local control in patients undergoing head and neck cancer surgeries. Further research with larger cohorts is necessary to confirm these findings.
背景：本研究评估了三维（3D）打印引导下上颌骨切除术与传统上颌骨切除术对头颈癌患者手术精准度及肿瘤学结局的影响。材料与方法：对42例接受上颌骨切除术的患者（16例采用3D打印引导，26例采用传统术式）进行回顾性分析，比较患者人口学特征、肿瘤特点及临床结局，并采用Kaplan-Meier法分析生存结局。结果：与传统组相比，3D打印组的切缘阴性率更高（81.3% vs. 76.9%），且在5年局部无复发生存率（87.5% vs. 58.7%）和总生存率（84.4% vs. 70.1%）方面均呈现改善趋势，但差异未达到统计学显著性。结论：3D打印引导的上颌骨切除术可能提升头颈癌手术的精准度并改善局部控制效果，但需通过更大样本量的研究进一步验证。
肿瘤(癌症)患者之家