Background: Sarcomas are a rare, complex group of malignancies characterized by numerous clinical and pathological features. Sarcomas originate from various tissues such as fat, muscle, bone, nerves, blood vessels and connective tissues. Typically, the treatment of sarcomas consists of surgery, chemotherapy, and radiation therapy. The location, type, stage, and treatment of sarcomas contribute to the development of physical impairments affecting joint and limb function, peripheral nerves, strength, and mobility, diminishing physical function and quality of life. Traditionally, rehabilitative therapy has been implemented after cancer treatment to help improve physical impairments imparted from cancer therapy. Recent work in rehabilitative medicine has explored the implementation of rehabilitative therapy prior to beginning cancer treatment (pre-habilitation) to help mitigate the detrimental physical consequences seen in sarcoma patients. Objective: The objective of this narrative review is to examine the physical impairments affecting sarcoma patients after cancer therapy and the impact of rehabilitative medicine on physical function and quality of life when implemented before and after cancer treatment.
背景:肉瘤是一类罕见且复杂的恶性肿瘤,具有多种临床和病理学特征。肉瘤起源于脂肪、肌肉、骨骼、神经、血管及结缔组织等多种组织。通常,肉瘤的治疗包括手术、化疗和放疗。肉瘤的部位、类型、分期及治疗方式会导致影响关节与肢体功能、周围神经、肌力和活动能力的身体损伤,从而降低身体功能和生活质量。传统上,康复治疗通常在癌症治疗后实施,以帮助改善癌症治疗带来的身体损伤。近期康复医学的研究探索了在开始癌症治疗前实施康复治疗(预康复)的方法,以帮助减轻肉瘤患者所经历的有害身体后果。 目的:本叙述性综述旨在探讨癌症治疗后影响肉瘤患者的身体损伤,以及康复医学在癌症治疗前后实施时对身体功能和生活质量的影响。