Background: Breast cancer is the most common cancer among women. The number of cases is increasing among young women, and consequently, breast reconstructions are performed more often. Postoperative complications, wound healing, and the quality of scars influence the final cosmetic outcomes. The aim of the study was to investigate the effect of using a negative-pressure therapy compared to a standard dressing on two postoperative wounds in the same woman, after bilateral tissue expander replacement surgery—when identical healing conditions occur. Methods: This study includes a single-center evaluation of the application of two different dressings during bilateral exchanges of tissue expanders with breast implants. The study included 22 patients with a history of breast cancer after bilateral mastectomy with two-stage reconstruction. During the second stage, a sNPWT was applied to one breast and a standard dressing to the other. Results: A statistically significant difference in skin elasticity in favor of sNPWT was visible after 7 days, while the greatest difference was visible in the evaluation after 6 months (mean of 0.806 vs. 0.607). A difference in temperature measurements was shown 7 days after the procedure. However, after 30 days, these measurements were similar. There was also a reduced incidence of postoperative complications as well as seroma accumulation in the breasts with negative pressure. Conclusions: The results indicate faster healing, better scar quality, and improved skin elasticity in breasts with sNPWT compared to the standard dressing. The number of postoperative complications were also reduced, which is especially important in high-risk patients.
背景：乳腺癌是女性最常见的恶性肿瘤。年轻女性病例数量呈上升趋势，因此乳房重建手术日益频繁。术后并发症、伤口愈合情况及瘢痕质量直接影响最终美容效果。本研究旨在双侧组织扩张器置换术后，在相同愈合条件下，比较单侧使用负压伤口疗法与对侧使用标准敷料对双侧术后创面的影响差异。 方法：本研究为单中心评估，在双侧组织扩张器更换为乳房假体手术中应用两种不同敷料。纳入22例有乳腺癌病史的双侧乳房切除术后二期重建患者。在第二阶段手术中，单侧乳房应用单次使用负压伤口治疗系统，对侧乳房使用标准敷料。 结果：术后7天可见支持负压治疗组的皮肤弹性存在统计学显著差异，而最大差异出现在术后6个月评估时（均值0.806对比0.607）。术后7天温度测量显示组间差异，但30天后测量值趋于相似。负压治疗组术后并发症发生率及血清肿积聚情况均有所降低。 结论：研究结果表明，与传统标准敷料相比，负压伤口治疗能促进创面更快愈合、改善瘢痕质量并提升皮肤弹性。术后并发症数量的减少对高风险患者群体尤为重要。
肿瘤(癌症)患者之家