Background: The World Health Organisation reports that melanoma had an incidence of 331,722 cases worldwide in 2022, ranking it 17th on the list of the most prevalent malignancies. This disease is a threat to public health as years of potential life lost from melanoma deaths constitute an economic and social burden; it is, however, curable if detected early. This study aims to show current trends in clinical trials for melanoma screening. Materials and Methods: The analysis was conducted using data from clinicaltrials.gov. The analysis considered both interventional and observational studies on melanoma screening. Only the studies with complete and active statutes by 4 September 2024 were included in the analysis. Results: Out of 25 studies registered in clinical trial databases regarding melanoma screening, 20% research advanced imagining techniques employing innovative machine learning algorithms, while 16% explore behavioural interventions. Conclusions: Intensification of behavioural interventions and health promotion activities is recommended.
背景:世界卫生组织报告显示,2022年全球黑色素瘤新发病例达331,722例,位列最常见恶性肿瘤第17位。该疾病对公共卫生构成威胁,因其导致的潜在寿命损失年数造成社会经济负担;但若早期发现,该疾病可被治愈。本研究旨在揭示当前黑色素瘤筛查临床试验的发展趋势。 材料与方法:本研究基于ClinicalTrials.gov数据库数据进行分析,涵盖黑色素瘤筛查的干预性和观察性研究。仅纳入截至2024年9月4日状态完整且处于活跃状态的研究。 结果:在临床试验数据库中注册的25项黑色素瘤筛查研究中,20%采用创新机器学习算法探索先进成像技术,16%致力于行为干预研究。 结论:建议加强行为干预与健康促进活动的实施力度。