Contrast-enhanced mammography (CEM) uses intermittent dual-energy (low- and high-energy) exposures to produce low-energy mammograms and recombine enhanced images after the administration of iodized contrast medium, which provides more detailed information to detect breast cancers by using the features of morphology and abnormal uptake. In this article, we reviewed the literature to clarify the clinical applications of CEM, including (1) the fundamentals of CEM: the technique, radiation exposure, and image interpretation; (2) its clinical uses for cancer diagnosis, including problem-solving, palpable mass, suspicious microcalcification, architecture distortion, screening, and CEM-guided biopsy; and (3) the concerns of surgical oncology in pre-operative and neoadjuvant chemotherapy assessments. CEM undoubtedly plays an important role in clinical practice.
对比增强乳腺摄影（CEM）采用间歇性双能量（低能与高能）曝光技术，在注射碘对比剂后生成低能乳腺图像并重组增强影像，通过形态学特征与异常摄取特性提供更详尽的诊断信息以检测乳腺癌。本文通过文献综述系统阐述CEM的临床应用，包括：（1）技术原理：成像技术、辐射剂量及影像判读要点；（2）癌症诊断临床应用：针对疑难病例、可触及肿块、可疑微钙化、结构扭曲的鉴别诊断，筛查应用及CEM引导活检；（3）肿瘤外科关注领域：术前评估与新辅助化疗疗效监测。CEM在临床实践中无疑发挥着重要作用。
肿瘤(癌症)患者之家