Background:T-cell lymphomas (TCLs) are rare and aggressive malignancies associated with poor outcomes, often because of the development of acquired drug resistance as well as intolerance to the established and often toxic chemotherapy regimens in elderly and frail patients. The many subtypes of TCL are well established to exhibit marked geographic variation. The epidemiology, clinical presentation, diagnosis, prognosis, and treatment of TCLs in the Middle East (ME) are yet to be explored; hence, limited data are available about these entities in this part of the world.Aim: Therefore, in this review article, we aim to discuss the available data regarding the T-cell neoplasms in the ME, including the incidence of specific subtypes of peripheral T-cell lymphoma (PTCL), as well as the trends in survival and treatment, all in an effort to understand the natural history of these complex entities across the ME.
背景：T细胞淋巴瘤（TCLs）是一种罕见且侵袭性强的恶性肿瘤，其预后通常较差。这主要是由于老年和体弱患者常出现获得性耐药，以及对现有且通常具有毒性的化疗方案不耐受。TCL的多种亚型已明确表现出显著的地域差异。中东地区TCL的流行病学、临床表现、诊断、预后及治疗方法仍有待探索；因此，关于该地区这些疾病的数据十分有限。 目的：因此，在本篇综述文章中，我们旨在讨论中东地区T细胞肿瘤的现有数据，包括外周T细胞淋巴瘤（PTCL）特定亚型的发病率，以及生存和治疗趋势，以期全面了解中东地区这些复杂疾病的自然病程。
肿瘤(癌症)患者之家