Malignant tumors pose a significant global health challenge, severely threatening human health. Statistics from the World Health Organization indicate that, in 2022, there were nearly 20 million new cancer cases and 9.7 million cancer-related deaths. Therefore, it is urgently necessary to study the pathogenesis of cancer and explore effective diagnostic and treatment strategies. In recent years, research has highlighted the importance of mechanical cues in tumors, which have become a new hallmark of cancer and a key factor in regulating tumor behavior. This suggests that studying the mechanical properties of tumors may open potential new avenues for understanding the pathogenesis, diagnosis, and therapeutic intervention of cancer. This review summarizes the mechanical characteristics of tumors and the development of tumor diagnostics and treatments targeting specific mechanical factors. Finally, we propose new ideas and insights for the application of mechanomedicine in cancer diagnosis and treatment in the future.
恶性肿瘤是全球面临的重大健康挑战，严重威胁人类健康。世界卫生组织统计数据显示，2022年全球新发癌症病例近2000万例，癌症相关死亡达970万例。因此，亟需研究癌症的发病机制并探索有效的诊疗策略。近年来，研究强调了力学信号在肿瘤中的重要性，其已成为癌症的新标志，是调控肿瘤行为的关键因素。这表明，研究肿瘤的力学特性可能为理解癌症的发病机制、诊断和治疗干预开辟潜在的新途径。本综述总结了肿瘤的力学特征以及针对特定力学因素的肿瘤诊疗方法的发展。最后，我们为力学医学在未来癌症诊疗中的应用提出了新的思路和见解。
肿瘤(癌症)患者之家