Background/Objectives: The use of oral anticancer agents (OAA) dates to the late 20th century in cancer treatment. It is crucial that patients implement self-care behaviours to keep their disease stable and manage their OAA treatment. The three dimensions of self-care according to Riegel et al., self-care maintenance, self-care monitoring, and self-care management, may be implemented to avoid negative outcomes. This paper seeks to identify outcomes associated with self-care in breast cancer patients during treatment with OAA and to compare which of these outcomes fall into the core outcome categorizations in oncology (minimal set of outcomes that research on a given health issue should measure). Methods: A systematic review with narrative synthesis was conducted. This study included patients with breast cancer taking any kind of OAA and described outcomes of self-care. The search was performed on MEDLINE, Web of Science and CINAHL/PsycINFO; Results: Of 4173 records, eight studies were selected and reviewed. The core outcomes mainly considered were mortality, survival, disease recurrence and quality of life. All studies focused only on pharmacological adherence outcome; none of them focused on other dimensions of self-care. Conclusions: This systematic review highlighted that there is a great lack of research on outcomes related to self-care in patients with breast cancer taking OOA. Even though pharmacological adherence to OAA is important, other behaviours are also important to improve patients’ outcomes, but they have not been studied. Further research is needed to study how self-care behaviours can impact patients’ outcomes.
背景/目的：口服抗癌药物（OAA）在癌症治疗中的应用可追溯至20世纪末。患者实施自我护理行为对于维持疾病稳定和管理OAA治疗至关重要。根据Riegel等人的理论，自我护理的三个维度——自我护理维持、自我护理监测和自我护理管理——可用于避免不良结局。本文旨在识别乳腺癌患者在接受OAA治疗期间与自我护理相关的结局，并比较这些结局中哪些属于肿瘤学核心结局分类（即针对特定健康问题的研究应测量的最小结局集）。方法：本研究进行了系统综述与叙述性综合。纳入对象为接受任何类型OAA治疗的乳腺癌患者，并描述了自我护理的结局。检索数据库包括MEDLINE、Web of Science和CINAHL/PsycINFO。结果：在4173条记录中，筛选出8项研究进行综述。主要关注的核心结局包括死亡率、生存率、疾病复发和生活质量。所有研究仅聚焦于药物依从性结局，未涉及自我护理的其他维度。结论：本系统综述揭示，目前极度缺乏针对接受OAA治疗的乳腺癌患者自我护理相关结局的研究。尽管OAA的药物依从性至关重要，但其他自我护理行为对改善患者结局同样重要，却尚未得到充分研究。未来需进一步探讨自我护理行为如何影响患者结局。
肿瘤(癌症)患者之家