文章：

实施高质量亚肺叶切除术：楔形切除术与肺段切除术的关键差异

Performing High-Quality Sublobar Resections: Key Differences Between Wedge Resection and Segmentectomy

原文发布日期：27 November 2024

DOI: 10.3390/cancers16233981

类型: Article

开放获取: 是

英文摘要：

Lung cancer remains the leading cause of cancer-related deaths worldwide. The introduction of targeted treatments and immunotherapy in lung cancer has transformed patient care by offering “precision medicine” focused on the characteristics of the disease. The same concept has emerged in lung cancer surgery. This “precision surgery” aims to determine the best surgical approach based on the characteristics of the cancer, the patient’s cardiorespiratory status, and technological advances in thoracic surgery. While lobectomy continues to be the gold standard for managing early-stage lung cancer, the implementation of screening programs has enabled the earlier detection of smaller tumors. In this context, sublobar resections, particularly segmentectomy, have emerged as valuable options in the treatment of early-stage lung cancer. Recent studies suggest that sublobar resections, including segmentectomy and wedge resection, provide a viable alternative to lobectomy. This review explores the various resection strategies available, tailored to patient and tumor characteristics, and highlights modern preoperative techniques aimed at advancing precision surgery.

摘要翻译： 

肺癌仍是全球癌症相关死亡的首要原因。靶向治疗和免疫疗法的引入，通过针对疾病特征的"精准医疗"改变了肺癌患者的治疗模式。这一理念同样在肺癌外科领域兴起。"精准外科"旨在根据肿瘤特征、患者心肺功能状态以及胸外科技术进步，确定最佳手术方案。虽然肺叶切除术仍是早期肺癌治疗的金标准，但筛查项目的实施使得更小的肿瘤得以早期发现。在此背景下，亚肺叶切除术（尤其是肺段切除术）已成为早期肺癌治疗的重要选择。最新研究表明，包括肺段切除术和楔形切除术在内的亚肺叶切除术可作为肺叶切除术的有效替代方案。本文综述了针对患者和肿瘤特征制定的不同切除策略，并重点介绍了推动精准外科发展的现代术前定位技术。

原文链接：

Performing High-Quality Sublobar Resections: Key Differences Between Wedge Resection and Segmentectomy