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文章:

手部内生软骨瘤患者中基于骨缺损填充松质异体骨移植程度的结果差异

Differences in Outcomes Based on the Degree to Which Bone Defects Are Filled with Cancellous Allochip Bone Grafts in Hand Enchondroma Patients

原文发布日期:13 November 2024

DOI: 10.3390/cancers16223811

类型: Article

开放获取: 是

 

英文摘要:

Background/Objectives: Enchondroma, the most common benign cartilage tumor in the hand, often presents as pain, swelling, or pathological fractures. While curettage is the standard treatment preventing fractures, the optimal way of managing the bone cavity remains debated. In this study, we investigated the impact of a filled bone defect on radiologic and clinical outcomes among patients with enchondroma. Methods: We retrospectively reviewed patients with solitary enchondroma of the hand who underwent curettage followed by allogeneic cancellous bone chip impaction grafting. The patients were divided into two groups based on the extent to which their bone defects were filled post-curettage: Group 1 (complete filling) and Group 2 (incomplete filling, i.e., <50%). We reviewed demographic data, local recurrence data, complications, information on consolidation duration, data on range of motion (ROM), and functional scores. Results: This study included 59 patients (25 males and 34 females; mean age, 30.4 ± 11.9 years, with a range of 8–78). Group 1 contained 35 patients, and Group 2 contained 24. No nonunion occurred following curettage and grafting. The mean radiological consolidation period was 6.4 weeks (range: 5–18). There was no significant difference in consolidation time between Group 1 (6.8 weeks) and Group 2 (6.9 weeks) (p= 0.166). The ROM and functional scores also showed no significant differences between the groups, with musculoskeletal society scores of 98.8 for Group 1 and 99.8 for Group 2 (p= 0.63). Conclusions: This study demonstrates that the use of the impaction technique combined with cancellous allochip bone grafting yields favorable results in the treatment of solitary hand enchondroma. The extent to which the bone defect was filled did not significantly impact the overall outcomes.

 

摘要翻译: 

背景/目的:内生软骨瘤是手部最常见的良性软骨肿瘤,常表现为疼痛、肿胀或病理性骨折。虽然刮除术是预防骨折的标准治疗方法,但骨缺损腔的处理方式仍存在争议。本研究旨在探讨骨缺损填充程度对手部内生软骨瘤患者影像学及临床预后的影响。方法:我们回顾性分析了接受刮除术联合同种异体松质骨碎块打压植骨治疗的孤立性手部内生软骨瘤患者。根据刮除术后骨缺损填充程度将患者分为两组:第1组(完全填充)和第2组(不完全填充,即填充率<50%)。收集并分析患者的人口统计学资料、局部复发情况、并发症、骨愈合时间、关节活动度及功能评分数据。结果:本研究共纳入59例患者(男性25例,女性34例;平均年龄30.4±11.9岁,范围8-78岁)。第1组35例,第2组24例。所有患者刮除植骨术后均未出现骨不连。影像学骨愈合平均时间为6.4周(范围:5-18周)。第1组(6.8周)与第2组(6.9周)的骨愈合时间无显著差异(p=0.166)。两组患者的关节活动度及功能评分亦无显著差异,肌肉骨骼协会评分第1组为98.8分,第2组为99.8分(p=0.63)。结论:本研究表明,采用打压植骨技术联合同种异体松质骨移植治疗孤立性手部内生软骨瘤可获得良好疗效。骨缺损的填充程度对总体预后无显著影响。

 

原文链接:

Differences in Outcomes Based on the Degree to Which Bone Defects Are Filled with Cancellous Allochip Bone Grafts in Hand Enchondroma Patients

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