Endometrial cancer is the most frequently diagnosed gynecological cancer. The aim of this study was to summarize and compare the most recent guidelines regarding its management. A comparative review of guidelines from the European Society of Gynecological Oncology, the European Society for Radiotherapy and Oncology, the European Society of Pathology, the European Society for Medical Oncology, the Cancer Council of Australia, the British Gynecological Cancer Society, the National Comprehensive Cancer Network, and the American College of Obstetricians and Gynecologists was carried out. The comparison of guidelines highlighted common recommendations and key differences regarding the most basic aspects of endometrial cancer management. Certain differences were identified in the options of surgical procedures based on endometrial biopsy and lymph node infiltration. Minor differences were identified in the management of recurrent disease, while the more pronounced differences were found in the follow-up procedure. The development of consistent international protocols in similar resource settings may lead to a more consistent classification, as well as to common lines regarding surgical approaches, risk stratification and the way patients should be monitored following the remission of endometrial cancer.
子宫内膜癌是最常被诊断的妇科恶性肿瘤。本研究旨在总结并比较其治疗相关的最新指南。我们对欧洲妇科肿瘤学会、欧洲放射治疗与肿瘤学会、欧洲病理学会、欧洲肿瘤内科学会、澳大利亚癌症委员会、英国妇科癌症学会、美国国家综合癌症网络以及美国妇产科医师学会发布的指南进行了比较性综述。通过对比发现，各指南在子宫内膜癌治疗最基本层面存在共同建议与关键分歧。具体而言，基于子宫内膜活检和淋巴结浸润情况的手术方案选择存在差异，复发疾病的管理策略存在细微差别，而随访程序的差异更为显著。在相似医疗资源条件下制定统一的国际诊疗方案，将有助于实现更一致的疾病分类，并在手术方式、风险分层及缓解期患者监测方案等方面形成共识性规范。
Management of Endometrial Cancer: A Comparative Review of Guidelines
肿瘤(癌症)患者之家