Introduction:Analysis of selected MRI parameters in initial MRI for the characterization of ovarian masses enables differentiation between mucinous ovarian carcinoma and metastatic ovarian tumors.Material and Methods:A prospective analysis of contrast-enhanced MRI of patients with suspected ovarian masses diagnosed in ultrasound and CT examination. Morphological criteria, such as the size of lesion, bilateral location, presence of “mille-feuille sign”, so-called Seidman criteria, as well as the diffusion weighted imaging and dynamic contrast enhancement of each lesion, were evaluated. Patients were allocated into two groups; the first group contained patients with mucinous ovarian cancer, and the second group contained patients with metastatic ovarian tumors.Results:A total of 35 patients were enrolled into the study. Median age was 49 in the first group and 59 in the second group of patients (p= 0.04). In the first group, all patients (100%) had unilateral lesions, and in the second group, 94% had bilateral tumors (p< 0.000001). In the first group, a tumor size equal or greater than 10 cm was present in 80% of patients, and the same was true for 21% of patients in the second group. The mille-feuille sign was present in 30% of patients from the first group and in 64% of patients from the second group. In the first group of patients, TTP was 410 and Perf.Max Enhancement was 141; in the second group, they were, respectively, 154 and 167 (p= 0.0001 andp= 0.5). Median ADC values in the first group were significantly higher in the first group than in the second group (p< 0.01).Conclusions:Significant differences in TTP and ADC values as well as in Seidman criteria enable reliable differentiation between the analyzed groups of tumors.
引言：通过分析初次磁共振成像中选定的参数来表征卵巢肿块，能够区分黏液性卵巢癌与卵巢转移性肿瘤。 材料与方法：本研究对经超声和CT检查诊断为可疑卵巢肿块的患者进行了对比增强磁共振成像的前瞻性分析。评估的形态学标准包括病灶大小、双侧性位置、"千层饼征"的存在、所谓的Seidman标准，以及各病灶的弥散加权成像和动态对比增强特征。患者被分为两组：第一组为黏液性卵巢癌患者，第二组为卵巢转移性肿瘤患者。 结果：共有35例患者纳入研究。第一组患者中位年龄为49岁，第二组为59岁（p=0.04）。第一组所有患者（100%）均为单侧病灶，而第二组94%为双侧肿瘤（p<0.000001）。在第一组中，80%的患者肿瘤大小≥10厘米，而第二组仅有21%的患者达到此标准。"千层饼征"在第一组患者中出现率为30%，在第二组中为64%。第一组患者的达峰时间（TTP）为410，最大灌注增强值为141；第二组分别为154和167（p=0.0001和p=0.5）。第一组患者的表观弥散系数（ADC）中位数显著高于第二组（p<0.01）。 结论：达峰时间、表观弥散系数值以及Seidman标准在两组肿瘤间存在显著差异，这些指标能够可靠区分所分析的肿瘤类型。
肿瘤(癌症)患者之家