Background: Different approaches are required in treating patients with multiple pulmonary lesions. A multistage procedure may increase the risk of complications and patient discomfort. This study reports an initial experience with single-stage management of multiple lung lesions using percutaneous ablation with thoracoscopic resection in a hybrid operating room (HOR). Methods: We retrospectively evaluated patients who underwent combined ablation and resection in an HOR between May 2022 and July 2024. All patients received a single anesthesia via endotracheal tube intubation. The clinical data, operative findings, and pathological characteristics of the lung nodules were recorded. Results: A total of 22 patients were enrolled in this study. Twenty patients underwent unilateral procedures, while the other two patients underwent bilateral procedures. Ablations were performed before lung resection in 21 patients; only 1 patient underwent surgery first. The median global operating room time was 227.0 min. The median total radiation dose (dose area product) was 14,076 μGym2. The median hospital postoperative length of stay was 2 days. Conclusions: The single-stage procedure of percutaneous ablation with thoracoscopic resection under general anesthesia in an HOR is feasible and safe. This procedure is an alternative method for managing multiple pulmonary lesions.
背景:治疗多发性肺结节患者需采用不同策略。分期手术可能增加并发症风险及患者不适。本研究报道了在复合手术室(HOR)中采用经皮消融联合胸腔镜切除术单次处理多发性肺结节的初步经验。方法:回顾性分析2022年5月至2024年7月期间在复合手术室接受消融联合切除术的患者资料。所有患者均通过气管插管接受单次全身麻醉。记录肺结节的临床资料、术中发现及病理特征。结果:共纳入22例患者,其中20例接受单侧手术,2例接受双侧手术。21例患者先行消融后行肺切除,仅1例患者先行手术。中位手术室总时间为227.0分钟,中位总辐射剂量(剂量面积乘积)为14,076 μGym²,术后中位住院时间为2天。结论:在复合手术室全身麻醉下实施经皮消融联合胸腔镜切除术的单阶段治疗方案安全可行,为处理多发性肺结节提供了新的治疗选择。