文章：

睾丸癌差异研究：文献综述

Disparities in Testicular Cancer: A Review of the Literature

原文发布日期：10 October 2024

DOI: 10.3390/cancers16203433

类型: Article

开放获取: 是

英文摘要：

Background: Testicular cancer is the most common malignancy diagnosed in adolescents and young adults, and evidence has emerged regarding disparities that affect different groups of patients.Methods: In this article, we conducted a thorough review of this area and summarized the existing literature.Results: Some of the pertinent findings from our review include poorer outcomes for various groups including the native Māori population of New Zealand, those who live in the United States–Mexico border region, those who live in Eastern Europe, those who are uninsured and those with poorer socioeconomic status, amongst others. In the United States specifically, there is significant evidence showing that racial/ethnic minorities, compared to white patients, tend to fare worse with later presentation at higher stages and worse survival rates. Hispanic patients in particular appear to have the potential for more aggressive tumor biology than other groups and are projected to have the highest incidence rates in the US by 2026.Conclusions: Overall, disparities exist in many aspects of testicular cancer and are striking in some instances, and further research is needed in this arena and in potential solutions.

摘要翻译： 

背景：睾丸癌是青少年和年轻成人中最常见的恶性肿瘤，现有证据表明不同患者群体之间存在显著差异。 方法：本文对该领域进行了系统综述，并对现有文献进行了归纳总结。 结果：综述发现多个群体预后较差，包括新西兰原住民毛利人、美国-墨西哥边境地区居民、东欧居民、无医疗保险者以及社会经济地位较低者等。特别是在美国，大量证据表明少数族裔患者相较于白人患者往往就诊时分期更晚、生存率更低。其中西班牙裔患者可能具有更具侵袭性的肿瘤生物学特征，预计到2026年将成为美国睾丸癌发病率最高的群体。 结论：睾丸癌在多个层面存在差异，部分差异尤为显著，该领域及潜在解决方案亟待进一步研究。

原文链接：

Disparities in Testicular Cancer: A Review of the Literature